v3.25.1
Document and Entity Information - shares
3 Months Ended
Mar. 31, 2025
May 08, 2025
Cover [Abstract]    
Document Type 10-Q  
Amendment Flag false  
Document Period End Date Mar. 31, 2025  
Document Fiscal Year Focus 2025  
Document Fiscal Period Focus Q1  
Trading Symbol CUE  
Entity Registrant Name Cue Biopharma, Inc.  
Entity Central Index Key 0001645460  
Current Fiscal Year End Date --12-31  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Interactive Data Current Yes  
Document Transition Report false  
Title of 12(b) Security Common Stock, par value $0.001 per share  
Security Exchange Name NASDAQ  
Entity Incorporation, State or Country Code DE  
Document Quarterly Report true  
Entity Emerging Growth Company false  
Entity Common Stock, Shares Outstanding   75,349,881
Entity Current Reporting Status Yes  
Entity Shell Company false  
Entity File Number 001-38327  
Entity Tax Identification Number 47-3324577  
Entity Address, Address Line One 40 Guest Street  
Entity Address, City or Town Boston  
Entity Address State or Province MA  
Entity Address, Postal Zip Code 02135  
City Area Code 617  
Local Phone Number 949-2680