v3.25.1
LICENSES AND AGREEMENTS (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
May 18, 2023
USD ($)
item
Jul. 31, 2024
USD ($)
Oct. 31, 2022
item
Apr. 30, 2017
USD ($)
Nov. 30, 2016
item
Aug. 31, 2011
Mar. 31, 2025
USD ($)
Mar. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2020
USD ($)
Research and development             $ 76,879 $ 79,783    
Through the end of 2024                    
Quarterly payment for research and development   $ 500                
Commencing in 2025 and end of agreement term                    
Quarterly payment for research and development   $ 900                
Strategic Alliance Agreement                    
Research and development             0 400    
Research and development arrangement, contract to perform for others, costs incurred, gross       $ 5,300            
Maximum | Strategic Alliance Agreement                    
Research and development arrangement, contract to perform for others, costs incurred, gross       $ 14,200            
Sponsored research agreement                    
Research and development             100 100    
First WuXi Manufacturing and Services Agreement                    
Number Of Suites Under The Agreement | item         2          
Second WuXi Manufacturing and Services Agreement                    
Agreement term     3 years              
Number Of Suites Under The Agreement | item     2              
Patent license agreement related to the development and manufacture of TIL therapies                    
Amount of collaborative arrangement required to be remitted             $ 1,500      
Period of collaborative arrangement required to be remitted             60 days      
License agreement             $ 200      
Second Amended and Restated Patent License Agreement                    
Amount of collaborative arrangement required to be remitted             $ 6,000      
Period of collaborative arrangement required to be remitted             60 days      
Phase 2 Clinical Study in Melanoma                    
Amount of collaborative arrangement required to be remitted                 $ 600  
Period of collaborative arrangement required to be remitted                 60 days  
Cooperative Research and Development Agreement                    
Agreement term   5 years       5 years        
Research and development             $ 900 500    
Notification period to terminate agreement   60 days                
WuXi Apptech, Inc - Manufacturing and Services Agreement                    
Research and development             8,400 5,500    
Cellectis S.A                    
Research and development             100 100    
Novartis Pharma AG and Related Entities - License Agreement                    
Research and development               0   $ 10,000
Patient dosing initiation expenses             2,500      
Number of historical asset purchase agreement. | item 2                  
Number of historical master cell bank license and working cell bank transfer agreement | item 1                  
Number of historical license agreement | item 1                  
Amount of milestone payment made during the period under the license agreement             $ 0 $ 0    
Percent of milestone payments reimbursable 25.00%                  
Novartis Pharma AG and Related Entities - License Agreement | Maximum | UNITED STATES                    
Amount of milestone payments payable under the license agreement $ 30,000                  
Novartis Pharma AG and Related Entities - License Agreement | Maximum | Non-US                    
Amount of milestone payments payable under the license agreement $ 15,000