v3.25.1
Commitments and Contingencies (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Oct. 02, 2024
Jul. 14, 2023
Jun. 30, 2023
Mar. 31, 2025
Oct. 31, 2024
Non-cancelable commitments for product manufacturing and supply costs       $ 20,400  
Pharmosa License Agreement          
Upfront license fee to be paid     $ 10,000    
Accrued additional upfront license fee         $ 3,500
Maximum potential development milestone payments $ 37,750        
Milestone payment for each additional indication approved by the FDA after PAH and PH-ILD and each additional product approved by the FDA under the license 10,000        
Milestone payment for each additional indication approved by the EMA after PAH and PH-ILD 2,000        
Milestone payment for each additional indication approved by the PMDA after PAH and PH-ILD 500        
Pharmosa License Agreement | North America          
Maximum potential sales milestones 185,000        
Pharmosa License Agreement | Other then North America          
Maximum potential sales milestones $ 150,000        
Chasm Technologies          
Maximum future contingent milestones and royalties       1,500  
Accrued contingent milestones and royalties       200  
Agreement With LGM Pharma, LLC          
Purchase Commitment, Remaining Minimum Amount Committed       $ 2,700  
Expiration term of agreement       5 years  
Amended and Restated Commercial Manufacturing Services and Supply Agreement with Lonza Tampa LLC          
Termination term for FDA rejection   60 days      
Termination term for FDA delay   120 days      
Percentage of reimburse   50.00%      
Aggregate exceed   $ 2,500      
Term of submission   24 months      
Initial term   12 months