v3.25.1
Segment Information - Schedule of Segment Revenue, Segment Profit or Loss and Significant Segment Expenses (Detail) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Less:    
Interest income $ (2,658) $ (3,303)
Interest expense 11,049 6,967
Income tax expense 341 170
Net loss (92,225) (66,423)
Reported Segment [Member]    
Segment Reporting Information [Line Items]    
Revenue 166,797 172,325
Less:    
Internal research and development costs 22,950 19,724
Internal selling, general and administrative costs 46,668 46,339
External commercial costs 56,993 58,672
External research and development costs 51,720 50,992
External general and administrative costs 10,060 8,129
Other segment items [1] 34,525 20,709
Share-based compensation expense 27,374 30,349
Interest income (2,658) (3,303)
Interest expense 11,049 6,967
Income tax expense 341 170
Net loss $ (92,225) $ (66,423)
[1] Other segment items include cost of sales, and other expenses.