SEGMENT INFORMATION - Schedule of Expenses by Segment (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Segment Reporting Information [Line Items]
Total research and development expense	$ 265,122	$ 260,995
Total selling, general and administrative expense	239,949	210,797
Compensation and related
Segment Reporting Information [Line Items]
Total selling, general and administrative expense	131,437	117,341
Consulting and professional services
Segment Reporting Information [Line Items]
Total selling, general and administrative expense	64,687	56,759
Occupancy and all other costs
Segment Reporting Information [Line Items]
Total selling, general and administrative expense	43,825	36,697
Clinical research and outside services
Segment Reporting Information [Line Items]
Total research and development expense	127,343	125,510
Compensation and related
Segment Reporting Information [Line Items]
Total research and development expense	99,187	96,424
Occupancy and all other costs
Segment Reporting Information [Line Items]
Total research and development expense	$ 38,592	$ 39,061