| | | | | | | | |
| Name of Subsidiary | | Jurisdiction of Incorporation or Organization |
| AM BD GP JV, S.A.P.I. de C.V. * | | Mexico |
| Badurey S.A. | | Uruguay |
| Click Hoteles.com, LLC | | Delaware, United States of America |
| Decolar.com Ltda. | | Brazil |
| Decolar.com, Inc. | | Delaware, United States of America |
| Despegar Colombia S.A.S. | | Colombia |
| DespegarEcuador S.A. | | Ecuador |
| Despegar.com Chile SpA. | | Chile |
| Despegar.com México, S.A. de C.V. | | Mexico |
| Despegar.com Perú S.A.C. | | Peru |
| Despegar.com USA, Inc. | | Delaware, United States of America |
| Despegar.com.ar S.A. | | Argentina |
| DFinance Holding Ltda. | | Brazil |
| Holidays S.A. | | Uruguay |
| Jamiray International S.A. * | | Uruguay |
| Koin Administradora de Cartões e Meios de Pagamento S.A. | | Brazil |
| Koin (BVI) Limited | | British Virgin Islands |
| Rivamor S.A. | | Uruguay |
| Ruotej S.A. | | Uruguay |
| Ruselmy S.A. | | Uruguay |
| Satylca S.C.A. | | Uruguay |
| Servicios Online 3351 de Venezuela C.A. | | Venezuela |
| South Net Turismo S.A.U. | | Argentina |
| Stays S.A. | | Brazil |
| Travel Reservations S.R.L. | | Uruguay |
| Viajes Beda, S.A. de C.V. | | Mexico |
| Xirex Contigo S.A.P.I. de C.V. SOFOM, E.N.R. | | Mexico |