Accrued Expenses (Details) - USD ($) $ in Thousands |
Dec. 31, 2022 |
Sep. 30, 2022 |
Jun. 30, 2022 |
Mar. 31, 2022 |
Dec. 31, 2021 |
|---|---|---|---|---|---|
| Payables and Accruals [Abstract] | |||||
| Product revenue allowances | $ 26,268 | $ 24,478 | |||
| Product return reserves, current portion | 7,789 | 6,704 | |||
| Accrued clinical trial expenses | 5,755 | 14,036 | |||
| Amounts due to collaboration partners | 0 | 22,654 | |||
| Accrued payroll and related expenses | 11,481 | 15,863 | |||
| Lease liabilities | $ 4,744 | $ 4,802 | |||
| Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] | Total accrued expenses | Total accrued expenses | |||
| Royalties | $ 3,804 | $ 3,472 | |||
| Professional fees | 1,886 | 1,899 | |||
| Accrued commercial manufacturing | 4,310 | 3,843 | |||
| Accrued restructuring | 2,751 | 0 | |||
| Accrued other | 6,989 | 11,263 | |||
| Total accrued expenses | $ 75,777 | $ 92,528 | $ 95,005 | $ 114,243 | $ 109,014 |
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- Definition Accrued clinical expenses current. No definition available.
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- Definition Accrued Commercial Manufacturing Current No definition available.
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- Definition Accrued product revenue allowances current. No definition available.
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- Definition Accrued Product Revenue Return Reserves, Current No definition available.
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- Definition Collaborative Arrangement Accrued Liability No definition available.
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- Definition Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Carrying value as of the balance sheet date of obligations incurred through that date and payable for royalties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Present value of lessee's discounted obligation for lease payments from operating lease, classified as current. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Indicates line item in statement of financial position that includes current operating lease liability. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- References No definition available.
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- Definition Carrying amount as of the balance sheet date of known and estimated obligations associated with exit from or disposal of business activities or restructurings pursuant to a duly authorized plan, which are expected to be paid in the next twelve months or in the normal operating cycle if longer. Costs of such activities include those for one-time termination benefits, termination of an operating lease or other contract, consolidating or closing facilities, relocating employees, and costs associated with an ongoing benefit arrangement, but excludes costs associated with the retirement of a long-lived asset. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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