v3.23.2
License, Collaboration and Other Significant Agreements - CSL Vifor License Agreement Narrative (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 22, 2022
USD ($)
shares
Feb. 18, 2022
USD ($)
Feb. 14, 2020
USD ($)
Apr. 08, 2019
USD ($)
May 31, 2017
USD ($)
$ / shares
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2022
USD ($)
performance_obligation
shares
Dec. 31, 2020
USD ($)
May 12, 2017
USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Upfront payment             $ 47,034    
Common stock, issued (in shares) | shares           177,000,963 184,135,714    
Refund liability to customer, amortization of discount             $ 3,400    
Refund liability to customer, amortization of deferred gain             $ 2,400    
Private Placement                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Sale of stock, issued in transaction (in shares) | shares 4,000,000                
Sale of stock, consideration received $ 20,000                
Aggregate net proceeds from offering, fair value in excess of carrying amount $ 13,600                
Vifor (International) Ltd.                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Contract termination, prior written notice period   30 months              
Vifor (International) Ltd.                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Contract termination, prior written notice period             6 months    
Refund liability to customer, gross             $ 40,000    
Refund liability to customer, noncurrent             $ 41,000    
Vifor (International) Ltd. | License                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Revenue, remaining performance obligation, profit share percentage   66.00%              
Upfront payment   $ 25,000              
Number of performance obligations | performance_obligation             1    
Refund liability to customer, purchase orders to total             50.00%    
Refund liability to customer, interest rate             15.00%    
Vifor (International) Ltd. | Research and development                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Collaboration purchase payment               $ 10,000  
Vifor (International) Ltd. | License Agreement                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Potential milestone revenue       $ 25,000          
Common stock, issued (in shares) | shares         3,571,429        
Sale of stock (in dollars per share) | $ / shares         $ 14.00        
Proceeds from common stock sold         $ 50,000        
Premium over the closing stock price of common stock (in dollars per share) | $ / shares         $ 12.69        
Premium amount over the closing stock price of common stock         $ 4,700       $ 4,700
Vifor (International) Ltd. | Priority Review Voucher Letter Agreement                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                  
Proceeds from collaborators     $ 10,000     $ 8,600