v3.23.1
Schedule of Warrants Outstanding (Details)
 12 Months Ended
Dec. 31, 2022
$ / shares
shares
Warrant One [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Dec. 17, 2021
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 14.99
Warrants, Expiration Date Dec. 15, 2026
Number of Shares Underlying Warrants 36,538
Number of shares underlying exercisable warrants 36,538
Warrant Two [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Dec. 17, 2021
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 13.99
Warrants, Expiration Date Dec. 17, 2026
Number of Shares Underlying Warrants 281,047
Number of shares underlying exercisable warrants 281,047
Warrant Three [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Feb. 16, 2021
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 49.99
Warrants, Expiration Date Feb. 11, 2026
Number of Shares Underlying Warrants 65,003
Number of shares underlying exercisable warrants 65,003
Warrant Four [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Aug. 07, 2020
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 35.99
Warrants, Expiration Date Jul. 14, 2025
Number of Shares Underlying Warrants 90,743
Number of shares underlying exercisable warrants 90,743
Warrant Five [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Aug. 07, 2020
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 44.99
Warrants, Expiration Date Jul. 14, 2025
Number of Shares Underlying Warrants 10,939
Number of shares underlying exercisable warrants 10,939
Warrant Six [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Jul. 23, 2020
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 35.99
Warrants, Expiration Date Jul. 14, 2025
Number of Shares Underlying Warrants 77,502
Number of shares underlying exercisable warrants 77,502
Warrant Seven [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Jul. 13, 2020
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 44.99
Warrants, Expiration Date Jul. 14, 2025
Number of Shares Underlying Warrants 21,846
Number of shares underlying exercisable warrants 21,846
Warrant Eight [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Jul. 13, 2020
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 35.99
Warrants, Expiration Date Jul. 14, 2025
Number of Shares Underlying Warrants 334,800
Number of shares underlying exercisable warrants 334,800
Warrant Nine [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Apr. 08, 2019
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 26.99
Warrants, Expiration Date Apr. 08, 2024
Number of Shares Underlying Warrants 65,907
Number of shares underlying exercisable warrants 65,907
Warrant Ten [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Apr. 08, 2019
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 33.74
Warrants, Expiration Date Apr. 03, 2024
Number of Shares Underlying Warrants 39,871
Number of shares underlying exercisable warrants 39,871
Warrant Eleven [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Feb. 12, 2019
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 36.62
Warrants, Expiration Date Feb. 07, 2024
Number of Shares Underlying Warrants 5,548
Number of shares underlying exercisable warrants 5,548
Warrant Twelve [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Feb. 12, 2019
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 26.79
Warrants, Expiration Date Aug. 12, 2024
Number of Shares Underlying Warrants 66,675
Number of shares underlying exercisable warrants 66,675
Warrant Thirteen [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Feb. 04, 2019
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 42.49
Warrants, Expiration Date Jan. 30, 2024
Number of Shares Underlying Warrants 1,732
Number of shares underlying exercisable warrants 1,732
Warrant Fourteen [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Jan. 31, 2019
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 42.49
Warrants, Expiration Date Jan. 26, 2024
Number of Shares Underlying Warrants 511
Number of shares underlying exercisable warrants 511
Warrant Fifteen [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Dec. 03, 2018
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 77.99
Warrants, Expiration Date Jun. 03, 2024
Number of Shares Underlying Warrants 46,876
Number of shares underlying exercisable warrants 46,876
Warrant Sixteen [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Apr. 03, 2018
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 149.99
Warrants, Expiration Date Apr. 03, 2023
Number of Shares Underlying Warrants 117,559
Number of shares underlying exercisable warrants 117,559
Warrant Seventeen [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Apr. 04, 2018
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 149.99
Warrants, Expiration Date Apr. 04, 2023
Number of Shares Underlying Warrants 5,751
Number of shares underlying exercisable warrants 5,751
Warrant Eighteen [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Warrants, Issue Date Jun. 15, 2015
Warrants, Classification Equity
Warrants, Exercise Price | $ / shares $ 1,509.99
Number of Shares Underlying Warrants 15,955
Number of shares underlying exercisable warrants
Warrants, Expiration Date, Description Five years after milestone achievement
Warrant [Member]  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]  
Number of Shares Underlying Warrants 1,284,803
Number of shares underlying exercisable warrants 1,268,848