v3.23.1
Cover - USD ($)
 12 Months Ended
Dec. 31, 2022
Mar. 15, 2023
Jun. 30, 2022
Document Information [Line Items]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2022    
Current Fiscal Year End Date --12-31    
Entity Transition Report false    
Entity File Number 001-04321    
Entity Registrant Name CENTESSA PHARMACEUTICALS PLC    
Entity Incorporation, State or Country Code X0    
Entity Tax Identification Number 98-1612294    
Entity Address, Address Line One 3rd Floor    
Entity Address, Address Line Two 1 Ashley Road    
Entity Address, Address Line Three Altrincham    
Entity Address, City or Town Cheshire    
Entity Address, Postal Zip Code WA14 2DT    
Entity Address, Country GB    
Country Region +44    
City Area Code 203    
Local Phone Number 9206789    
Extension 9999    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company true    
Entity Ex Transition Period false    
ICFR Auditor Attestation Flag false    
Entity Shell Company false    
Entity Public Float     $ 241,465,000
Entity Common Stock, Shares Outstanding   94,961,169  
Entity Central Index Key 0001847903    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Amendment Flag false    
Ordinary shares      
Document Information [Line Items]      
Title of 12(b) Security Ordinary shares, nominal value £0.002 per share    
Trading Symbol CNTA    
Security Exchange Name NASDAQ    
American Depositary Shares      
Document Information [Line Items]      
Title of 12(b) Security American Depositary Shares, each representing one ordinary share, nominal value £0.002 per share    
Trading Symbol CNTA    
Security Exchange Name NASDAQ