v3.23.1
Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2022
Mar. 15, 2023
Jun. 30, 2022
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2022    
Document Transition Report false    
Entity File Number 333-249434    
Entity Registrant Name Synaptogenix, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 46-1585656    
Entity Address, Address Line One 1185 Avenue of the Americas    
Entity Address, Address Line Two 3rd Floor    
Entity Address, City or Town New York    
Entity Address, State or Province NY    
Entity Address, Postal Zip Code 10036    
City Area Code 973    
Local Phone Number 242-0005    
Title of 12(b) Security Common Stock, $0.0001 par valueper share    
Trading Symbol SNPX    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company true    
Entity Ex Transition Period false    
ICFR Auditor Attestation Flag false    
Entity Shell Company false    
Entity Public Float     $ 35,193,727
Entity Common Stock, Shares Outstanding   7,355,371  
Auditor Name Morison Cogen LLP    
Auditor Location Blue Bell, PA    
Auditor Firm ID 536    
Entity Central Index Key 0001571934    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Amendment Flag false