Security
Type

Security
Class Title

Fee
Calculation
Rule

Amount
Registered (1)

Proposed
Maximum
Offering Price
Per Unit

Maximum
Aggregate
Offering Price

Fee Rate

Amount of
Registration Fee

Equity

Common
Stock,
$0.001
par value
per share

Other

4,225,859
shares (2)

$2.83 (3)

$11,959,181

(3)

$110.20

per $1,000,000

$1,317.91

Total Offering Amounts

$11,959,181

$1,317.91

Total Fee Offsets

$ 0

Net Fee Due

$1,317.91

(1)

In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.

(2)

Consists of 4,225,859 shares issuable under the Cue Biopharma, Inc. 2016 Omnibus Incentive Plan, as amended.

(3)

Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low prices of the Registrant’s Common Stock as reported on the Nasdaq Capital Market on March 14, 2023.