The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 13,649 857,338 SH SOLE 857,338 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 4,570 290,189 SH SOLE 290,189 0 0
ALLAKOS INC COM 01671P100 40,349 4,792,000 SH SOLE 4,792,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 21,945 2,985,757 SH SOLE 2,985,757 0 0
ANAPTYSBIO INC COM 032724106 27,882 899,700 SH SOLE 899,700 0 0
APTINYX INC COM 03836N103 537 1,883,244 SH SOLE 1,883,244 0 0
ARVINAS INC COM 04335A105 9,761 285,331 SH SOLE 285,331 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 7,119 3,746,857 SH SOLE 3,746,857 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 11,095 500,000 SH SOLE 500,000 0 0
Arcutis Biotherapeutics COM 03969K108 128,527 8,684,232 SH SOLE 8,684,232 0 0
BLUEBIRD BIO INC COM 09609G100 9,970 1,440,757 SH SOLE 1,440,757 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 12,395 393,000 SH SOLE 393,000 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 113,854 4,345,559 SH SOLE 4,345,559 0 0
COGENT BIOSCIENCES INC COM 19240Q201 24,382 2,109,154 SH SOLE 2,109,154 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 25,891 1,414,823 SH SOLE 1,414,823 0 0
ESSA Pharma, Inc. COM NEW 29668H708 1,525 605,141 SH SOLE 605,141 0 0
GRITSTONE BIO INC COM 39868T105 17,810 5,162,348 SH SOLE 5,162,348 0 0
HILLEVAX INC COM 43157M102 163,257 9,758,359 SH SOLE 9,758,359 0 0
IMAGO BIOSCIENCES INC COM 45250K107 143,340 3,987,207 SH SOLE 3,987,207 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 7,107 203,684 SH SOLE 203,684 0 0
Immunovant, Inc. COM 45258J102 10,397 585,759 SH SOLE 585,759 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 21,895 3,238,859 SH SOLE 3,238,859 0 0
KRYSTAL BIOTECH INC COM 501147102 79,199 999,737 SH SOLE 999,737 0 0
MERUS N V COM N5749R100 11,548 746,479 SH SOLE 746,479 0 0
Mirum Pharmaceuticals, Inc. COM 604749101 75,272 3,860,107 SH SOLE 3,860,107 0 0
NABRIVA THERAPEUTICS PLC SHS NEW 2022 G63637139 32 17,025 SH SOLE 17,025 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109 101,823 9,341,551 SH SOLE 9,341,551 0 0
NEWAMSTERDAM PHARMA COMPANY *W EXP 11/22/202 N62509117 434 500,333 SH SOLE 500,333 0 0
PROTHENA CORP PLC SHS G72800108 7,706 127,900 SH SOLE 127,900 0 0
Passage Bio, Inc. COM 702712100 5,185 3,756,915 SH SOLE 3,756,915 0 0
Phathom Pharmaceuticals, Inc. COM 71722W107 94,328 8,407,152 SH SOLE 8,407,152 0 0
REPLIMUNE GROUP INC COM 76029N106 25,338 931,560 SH SOLE 931,560 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 55,153 1,894,000 SH SOLE 1,894,000 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101 13,438 881,173 SH SOLE 881,173 0 0
SUTRO BIOPHARMA INC COM 869367102 14,354 1,776,479 SH SOLE 1,776,479 0 0
Syndax Pharmaceuticals, Inc. COM 87164F105 94,390 3,708,838 SH SOLE 3,708,838 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 6,963 1,398,194 SH SOLE 1,398,194 0 0
TREVI THERAPEUTICS INC COM 89532M101 12,861 6,663,590 SH SOLE 6,663,590 0 0
TYRA BIOSCIENCES INC COM 90240B106 10,090 1,327,665 SH SOLE 1,327,665 0 0
Tarsus Pharmaceuticals, Inc. COM 87650L103 26,205 1,787,527 SH SOLE 1,787,527 0 0
VECTIVBIO HLDG AG ORD SHS H9060V101 11,481 1,333,400 SH SOLE 1,333,400 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 73,575 2,815,720 SH SOLE 2,815,720 0 0
Vaxcyte, Inc. COM 92243G108 67,006 1,397,405 SH SOLE 1,397,405 0 0
ZYMEWORKS DEL INC COM 98985Y108 4,795 610,000 SH SOLE 610,000 0 0