Exhibit 99.2
BRISTOL-MYERS SQUIBB COMPANY
QUARTERLY TREND ANALYSIS OF REVENUES
(Unaudited, dollars in millions)
Revenues
2021
2022
% Change
FX Impact(b)
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYearQtr vs. QtrYTD vs. YTDQtr vs. QtrYTD vs. YTD
United States$7,010 $7,388 $14,398 $7,296 $21,694 $7,520 $29,214 $7,694 $8,268 $15,962 $7,941 $23,903 $7,925 $31,828 5 %9 %  
International3,899 4,124 8,023 4,052 12,075 4,244 16,319 3,727 3,427 7,154 3,062 10,216 3,281 13,497 (22)%(17)%(9)%(9)%
Other(a)
164 191 355 276 631 221 852 227 192 419 215 634 200 834 (10)%(2)%  
Total$11,073 $11,703 $22,776 $11,624 $34,400 $11,985 $46,385 $11,648 $11,887 $23,535 $11,218 $34,753 $11,406 $46,159 (5)% (4)%(3)%
% of Revenues
2021
2022
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear
United States63.3 %63.1 %63.2 %62.8 %63.1 %62.7 %63.0 %66.1 %69.6 %67.8 %70.8 %68.8 %69.5 %69.0 %
International35.3 %35.3 %35.2 %34.9 %35.1 %35.4 %35.1 %32.0 %28.8 %30.4 %27.3 %29.4 %28.8 %29.2 %
Other(a)
1.4 %1.6 %1.6 %2.3 %1.8 %1.9 %1.9 %1.9 %1.6 %1.8 %1.9 %1.8 %1.7 %1.8 %
Total100 %100 %100 %100 %100 %100 %100 %100 %100 %100 %100 %100 %100 %100 %
(a)    Other revenues include royalties and alliance-related revenues for products not sold by our regional commercial organizations.
(b)    Foreign exchange impacts were derived by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.

1


BRISTOL-MYERS SQUIBB COMPANY
EARNINGS FROM OPERATIONS
(Unaudited, dollars and shares in millions except per share data)
 
2021
2022
% Change
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYearQtr vs. QtrYTD vs. YTD
Net product sales$10,798 $11,405 $22,203 $11,243 $33,446 $11,609 $45,055 $11,308 $11,485 $22,793 $10,813 $33,606 $11,065 $44,671 (5)%(1)%
Alliance and other revenues275 298 573 381 954 376 1,330 340 402 742 405 1,147 341 1,488 (9)%12 %
Total Revenues11,073 11,703 22,776 11,624 34,400 11,985 46,385 11,648 11,887 23,535 11,218 34,753 11,406 46,159 (5)% 
Cost of products sold(a)
2,841 2,452 5,293 2,291 7,584 2,356 9,940 2,471 2,720 5,191 2,353 7,544 2,593 10,137 10 %2 %
Marketing, selling and administrative1,666 1,882 3,548 1,788 5,336 2,354 7,690 1,831 1,787 3,618 1,930 5,548 2,266 7,814 (4)%2 %
Research and development(b)
2,219 2,478 4,697 2,980 7,677 2,518 10,195 2,260 2,321 4,581 2,418 6,999 2,510 9,509  (7)%
Acquired IPRD(b)
793 799 271 1,070 89 1,159 333 400 733 30 763 52 815 (42)%(30)%
Amortization of acquired intangible assets2,513 2,547 5,060 2,546 7,606 2,417 10,023 2,417 2,417 4,834 2,418 7,252 2,343 9,595 (3)%(4)%
Other (income)/expense, net(702)(2)(704)(409)(1,113)393 (720)649 284 933 (140)793 (217)576 ****
Total Expenses8,543 10,150 18,693 9,467 28,160 10,127 38,287 9,961 9,929 19,890 9,009 28,899 9,547 38,446 (6)% 
Earnings before income taxes2,530 1,553 4,083 2,157 6,240 1,858 8,098 1,687 1,958 3,645 2,209 5,854 1,859 7,713  (5)%
Provision/(benefit) for income taxes501 492 993 605 1,598 (514)1,084 404 529 933 601 1,534 (166)1,368 (68)%26 %
Net Earnings2,029 1,061 3,090 1,552 4,642 2,372 7,014 1,283 1,429 2,712 1,608 4,320 2,025 6,345 (15)%(10)%
Noncontrolling interest14 20  20 13 15 3 18 N/A(10)%
Net Earnings Attributable to BMS$2,021 $1,055 $3,076 $1,546 $4,622 $2,372 $6,994 $1,278 $1,421 $2,699 $1,606 $4,305 $2,022 $6,327 (15)%(10)%
Diluted earnings per common share*$0.89 $0.47 $1.36 $0.69 $2.05 $1.07 $3.12 $0.59 $0.66 $1.25 $0.75 $2.00 $0.95 $2.95 (11)%(5)%
Weighted-average common shares outstanding - diluted2,265 2,252 2,258 2,243 2,253 2,219 2,245 2,164 2,149 2,157 2,148 2,154 2,124 2,146 
Dividends declared per common share$0.49 $0.49 $0.98 $0.49 $1.47 $0.54 $2.01 $0.54 $0.54 $1.08 $0.54 $1.62 $0.57 $2.19 6 %9 %
2021
2022
% of Total Revenues1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear
Gross margin74.3 %79.0 %76.8 %80.3 %78.0 %80.3 %78.6 %78.8 %77.1 %77.9 %79.0 %78.3 %77.3 %78.0 %
Other Ratios
Effective tax rate19.8 %31.7 %24.3 %28.0 %25.6 %(27.7)%13.4 %23.9 %27.0 %25.6 %27.2 %26.2 %(8.9)%17.7 %
Other (income)/expense, net
2021
2022
% Change
1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYearQtr vs. QtrYTD vs. YTD
Interest expense(c)
$353 $330 $683 $328 $1,011 $323 $1,334 $326 $313 $639 $299 $938 $294 $1,232 (9)% (8)%
Royalties and licensing income (232)(253)(485)(265)(750)(317)(1,067)(306)(287)(593)(374)(967)(316)(1,283) 20 %
Royalty income - divestiture(135)(152)(287)(160)(447)(219)(666)(171)(221)(392)(205)(597)(235)(832)7 %25 %
Equity investment losses/(income)(601)(148)(749)(465)(1,214)469 (745)644 308 952 14 966 (165)801 ** **
Integration expenses141 152 293 141 434 130 564 105 124 229 114 343 97 440 (25)% (22)%
Loss/(gain) on debt redemption281 — 281 — 281  281 275 (9)266 — 266  266 N/A (5)%
Divestiture (gains)/losses— (11)(11)(9) (9)(211)— (211)— (211) (211)N/A **
Investment income(9)(12)(21)(12)(33)(6)(39)(10)(27)(37)(52)(89)(82)(171)****
Litigation and other settlements(8)44 36 13 49 33 82 (37)25 (12)44 32 146 178 ** **
Provision for restructuring45 78 123 27 150 19 169 23 20 43 17 60 15 75 (21)%(56)%
Contingent consideration(510)— (510)— (510)(32)(542)— — (10)(9)(69)% (98)%
Other(27)(30)(57)(18)(75)(7)(82)10 38 48 51 39 90 ** **
Other (income)/expense, net$(702)$(2)$(704)$(409)$(1,113)$393 $(720)$649 $284 $933 $(140)$793 $(217)$576 ** **
*    Quarterly amounts may not add to the year-to-date amounts, as each period is computed on a discrete basis.
**    In excess of +/- 100%.
(a)    Excludes amortization of acquired intangible assets.
(b)    Research and development charges resulting from upfront or contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights have been reclassified to the Acquired IPRD line item beginning with the first quarter of 2022. Prior period results have been revised for comparability.
(c)    Includes amortization of purchase price adjustments to Celgene debt.


2


BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF GAAP AND NON-GAAP GROWTH DOLLARS AND PERCENTAGES EXCLUDING FOREIGN EXCHANGE IMPACT
FOR THE PERIOD ENDED DECEMBER 31, 2022
(Unaudited, dollars in millions)
QUARTER-TO-DATE
2022
2021
$ Change% ChangeFavorable/(Unfavorable) FX Impact $*2022 Excluding FXFavorable/(Unfavorable) FX Impact %*% Change Excluding FX
Revenues$11,406 $11,985 $(579)(5)%$(410)$11,816 (4)%(1)%
Gross profit8,813 9,629 (816)(8)%N/AN/AN/AN/A
Gross profit excluding specified items(a)
8,886 9,629 (743)(8)%N/AN/AN/AN/A
Gross profit excluding specified items as a % of revenues77.9 %80.3 %
Marketing, selling and administrative2,266 2,354 (88)(4)%70 2,336 %(1)%
Marketing, selling and administrative excluding specified items(a)
2,266 2,352 (86)(4)%70 2,336 %(1)%
Marketing, selling and administrative excluding specified items as a % of revenues19.9 %19.6 %
Research and development2,510 2,518 (8)— 28 2,538 %%
Research and development excluding specified items(a)
2,510 2,518 (8)— 28 2,538 %%
Research and development excluding specified items as a % of revenues22.0 %21.0 %
YEAR-TO-DATE
2022
2021
$ Change% ChangeFavorable/(Unfavorable) FX Impact $*2022 Excluding FXFavorable/(Unfavorable) FX Impact %*% Change Excluding FX
Revenues$46,159 $46,385 $(226)— $(1,464)$47,623 (3)%%
Gross profit36,022 36,445 (423)(1)%N/A N/A N/AN/A
Gross profit excluding specified items(a)
36,378 37,048 (670)(2)%N/A N/A N/AN/A
Gross profit excluding specified items as a % of revenues78.8 %79.9 %
Marketing, selling and administrative7,814 7,690 124 %207 8,021 %%
Marketing, selling and administrative excluding specified items(a)
7,735 7,687 48 %207 7,942 %%
Marketing, selling and administrative excluding specified items as a % of revenues16.8 %16.6 %
Research and development9,509 10,195 (686)(7)%102 9,611 %(6)%
Research and development excluding specified items(a)
9,201 9,352 (151)(2)%102 9,303 %(1)%
Research and development excluding specified items as a % of revenues19.9 %20.2 %
*    Foreign exchange impacts were derived by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.
(a)    Refer to the Specified Items schedule for further details.


3


BRISTOL-MYERS SQUIBB COMPANY
WORLDWIDE REVENUES
QUARTERLY REVENUES TREND ANALYSIS
(Unaudited, dollars in millions)
 
2021
2022
$ Change% Change
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYearQtr vs. QtrYTD vs. YTDQtr vs. QtrYTD vs. YTD
In-Line Products
Eliquis$2,886 $2,792 $5,678 $2,413 $8,091 $2,671 $10,762 $3,211 $3,235 $6,446 $2,655 $9,101 $2,688 $11,789 $17  $1,027 1 %10 %
Opdivo1,720 1,910 3,630 1,905 5,535 1,988 7,523 1,923 2,063 3,986 2,047 6,033 2,216 8,249 228 726 11 %10 %
Pomalyst/Imnovid773 854 1,627 851 2,478 854 3,332 826 908 1,734 886 2,620 877 3,497 23 165 3 %5 %
Orencia758 814 1,572 870 2,442 864 3,306 792 876 1,668 883 2,551 913 3,464 49 158 6 %5 %
Sprycel470 541 1,011 551 1,562 555 2,117 483 544 1,027 560 1,587 578 2,165 23 48 4 %2 %
Yervoy456 510 966 515 1,481 545 2,026 515 525 1,040 523 1,563 568 2,131 23 105 4 %5 %
Empliciti85 86 171 82 253 81 334 75 77 152 73 225 71 296 (10)(38)(12)%(11)%
Mature and other products(a)
506 473 979 480 1,459 441 1,900 462 435 897 441 1,338 411 1,749 (30)(151)(7)%(8)%
Total In-Line Products7,654 7,980 15,634 7,667 23,301 7,999 31,300 8,287 8,663 16,950 8,068 25,018 $8,322 33,340 323 2,040 4 %7 %
New Product Portfolio
Reblozyl112 128 240 160 400 151 551 156 172 328 190 518 199 717 48 166 32 %30 %
Abecma— 24 24 71 95 69 164 67 89 156 107 263 125 388 56 224 81 %**
Opdualag— —  —  —  —   58 64 84 148 104 252 104 252 N/AN/A
Zeposia18 28 46 40 86 48 134 36 66 102 69 171 79 250 31 116 65 %87 %
Breyanzi— 17 17 30 47 40 87 44 39 83 44 127 55 182 15 95 38 %**
Onureg15 12 27 21 48 25 73 23 32 55 32 87 37 124 12 51 48 %70 %
Inrebic16 16 32 22 54 20 74 18 23 41 21 62 23 85 3 11 15 %15 %
Camzyos— —  —  —  —   — 16 24 16 24 N/AN/A
Sotyktu— —  —  —  —   — — — 7 8 7 8 N/AN/A
Total New Product Portfolio161 225 386 344 730 353 1,083 350 482 832 553 1,385 645 2,030 292 947 83 %87 %
Total In-Line Products and New Product Portfolio7,815 8,205 16,020 8,011 24,031 8,352 32,383 8,637 9,145 17,782 8,621 26,403 8,967 35,370 615 2,987 7 %9 %
Recent LOE Products(b)
Revlimid2,944 3,202 6,146 3,347 9,493 3,328 12,821 2,797 2,501 5,298 2,420 7,718 2,260 9,978 (1,068)(2,843)(32)%(22)%
Abraxane314 296 610 266 876 305 1,181 214 241 455 177 632 179 811 (126)(370)(41)%(31)%
Total Recent LOE Products3,258 3,498 6,756 3,613 10,369 3,633 14,002 3,011 2,742 5,753 2,597 8,350 2,439 10,789 (1,194)(3,213)(33)%(23)%
Total$11,073 $11,703 $22,776 $11,624 $34,400 $11,985 $46,385 $11,648 $11,887 $23,535 $11,218 $34,753 $11,406 $46,159 $(579)$(226)(5)% 
**    In excess of +/- 100%.
(a)    Includes OTC products, royalty revenue and other mature products.
(b)    Recent LOE products include products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
4


BRISTOL-MYERS SQUIBB COMPANY
WORLDWIDE REVENUES
FOREIGN EXCHANGE IMPACT (%)
(Unaudited)
Three Months Ended December 31, 2022Twelve Months Ended December 31, 2022
Revenue Change %Favorable/ (Unfavorable) FX Impact % *Revenue Change % Excluding FXRevenue Change %Favorable/ (Unfavorable) FX Impact % *Revenue Change % Excluding FX
In-Line Products
Eliquis1%(5)%6%10%(4)%14%
Opdivo11%(5)%16%10%(4)%14%
Pomalyst/Imnovid3%(3)%6%5%(3)%8%
Orencia6%(3)%9%5%(3)%8%
Sprycel4%(4)%8%2%(4)%6%
Yervoy4%(5)%9%5%(5)%10%
Empliciti(12)%(5)%(7)%(11)%(4)%(7)%
Mature and other products(a)
(7)%(5)%(2)%(8)%(3)%(5)%
Total In-Line Products4%(5)%9%7%(4)%11%
New Product Portfolio
Reblozyl32%(2)%34%30%(2)%32%
Abecma81%(6)%87%******
OpdualagN/AN/AN/AN/AN/AN/A
Zeposia65%(4)%69%87%(6)%93%
Breyanzi38%(10)%48%******
Onureg48%(4)%52%70%(4)%74%
Inrebic15%15%15%(1)%16%
CamzyosN/AN/AN/AN/AN/AN/A
SotyktuN/AN/AN/AN/AN/AN/A
Total New Product Portfolio83%(4)%87%87%(5)%92%
Total In-Line Products and New Product Portfolio7%(5)%12%9%(4)%13%
Recent LOE Products(b)
Revlimid(32)%(1)%(31)%(22)%(1)%(21)%
Abraxane(41)%(2)%(39)%(31)%(1)%(30)%
Total Recent LOE Products(33)%(1)%(32)%(23)%(1)%(22)%
Total (5)%(4)%(1)%(3)%3%
*    Foreign exchange impacts were derived by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.
**    In excess of +/- 100%.
(a)    Includes over-the-counter (OTC) products, royalty revenue and other mature products.
(b)    Recent LOE products include products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
5


BRISTOL-MYERS SQUIBB COMPANY
U.S. REVENUES
QUARTERLY REVENUES TREND ANALYSIS
(Unaudited, dollars in millions)
 
2021
2022
% Change
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYearQtr vs. QtrYTD vs. YTD
In-Line Products
Eliquis$1,923 $1,722 $3,645 $1,315 $4,960 $1,496 $6,456 $2,147 $2,192 $4,339 $1,729 $6,068 $1,718 $7,786 15 %21 %
Opdivo944 1,076 2,020 1,062 3,082 1,120 4,202 1,099 1,205 2,304 1,243 3,547 1,265 4,812 13 %15 %
Pomalyst/Imnovid512 567 1,079 586 1,665 584 2,249 557 616 1,173 640 1,813 625 2,438 7 %8 %
Orencia536 593 1,129 644 1,773 637 2,410 592 654 1,246 682 1,928 710 2,638 11 %9 %
Sprycel275 325 600 346 946 351 1,297 305 372 677 402 1,079 418 1,497 19 %15 %
Yervoy294 328 622 313 935 330 1,265 311 326 637 322 959 345 1,304 5 %3 %
Empliciti51 51 102 48 150 50 200 47 47 94 47 141 44 185 (12)%(8)%
Mature and other products(a)
152 130 282 152 434 146 580 133 147 280 144 424 141 565 (3)%(3)%
Total In-Line Products4,687 4,792 9,479 4,466 13,945 4,714 18,659 5,191 5,559 10,750 5,209 15,959 5,266 21,225 12 %14 %
New Product Portfolio
Reblozyl98 110 208 147 355 130 485 134 144 278 156 434 157 591 21 %22 %
Abecma— 24 24 67 91 67 158 56 72 128 75 203 94 297 40 %88 %
Opdualag — — — —   58 64 84 148 104 252 N/AN/A
Zeposia13 20 33 32 65 34 99 21 48 69 50 119 58 177 71 %79 %
Breyanzi— 17 17 29 46 38 84 41 33 74 35 109 42 151 11 %80 %
Onureg14 12 26 21 47 22 69 19 25 44 24 68 27 95 23 %38 %
Inrebic15 15 30 20 50 17 67 15 20 35 17 52 17 69  3 %
Camzyos — — — —   — 16 24 N/AN/A
Sotyktu— — — — —   — — — 7 8 N/AN/A
Total New Product Portfolio140 198 338 316 654 308 962 292 403 695 447 1,142 522 1,664 69 %73 %
Total In-Line Products and New Product Portfolio4,827 4,990 9,817 4,782 14,599 5,022 19,621 5,483 5,962 11,445 5,656 17,101 5,788 22,889 15 %17 %
Recent LOE Products(b)
Revlimid1,958 2,164 4,122 2,303 6,425 2,270 8,695 2,038 2,130 4,168 2,170 6,338 2,021 8,359 (11)%(4)%
Abraxane225 234 459 211 670 228 898 173 176 349 115 464 116 580 (49)%(35)%
Total Recent LOE Products2,183 2,398 4,581 2,514 7,095 2,498 9,593 2,211 2,306 4,517 2,285 6,802 2,137 8,939 (14)%(7)%
Total(c)
$7,010 $7,388 $14,398 $7,296 $21,694 $7,520 $29,214 $7,694 $8,268 $15,962 $7,941 $23,903 $7,925 $31,828 5 %9 %
**    In excess of +/- 100%.
(a)    Includes OTC products, royalty revenue and other mature products.
(b)    Recent LOE Products include products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
(c)    Includes Puerto Rico.
6


BRISTOL-MYERS SQUIBB COMPANY
INTERNATIONAL REVENUES
QUARTERLY REVENUES TREND ANALYSIS
(Unaudited, dollars in millions)
2021
2022
% Change
1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYearQtr vs. QtrYTD vs. YTD
In-Line Products
Eliquis$963 $1,070 $2,033 $1,098 $3,131 $1,175 $4,306 $1,064 $1,043 $2,107 $926 $3,033 $970 $4,003 (17)%(7)%
Opdivo776 834 1,610 843 2,453 868 3,321 824 858 1,682 804 2,486 951 3,437 10 %3 %
Pomalyst/Imnovid261 287 548 265 813 270 1,083 269 292 561 246 807 252 1,059 (7)%(2)%
Orencia222 221 443 226 669 227 896 200 222 422 201 623 203 826 (11)%(8)%
Sprycel195 216 411 205 616 204 820 178 172 350 158 508 160 668 (22)%(19)%
Yervoy162 182 344 202 546 215 761 204 199 403 201 604 223 827 4 %9 %
Empliciti34 35 69 34 103 31 134 28 30 58 26 84 27 111 (13)%(17)%
Mature and other products(a)
354 343 697 328 1,025 295 1,320 329 288 617 297 914 270 1,184 (8)%(10)%
Total In-Line Products2,967 3,188 6,155 3,201 9,356 3,285 12,641 3,096 3,104 6,200 2,859 9,059 $3,056 $12,115 (7)%(4)%
New Product Portfolio
Reblozyl14 18 32 13 45 21 66 22 28 50 34 84 42 126 100 %91 %
Abecma— — — 2 6 11 17 28 32 60 31 91 ****
Zeposia13 21 14 35 15 18 33 19 52 21 73 50 %**
Breyanzi— — — 2 3 18 13 31 ****
Onureg— — 3 4 11 19 10 29 ****
Inrebic3 7 10 6 16 100 %**
Total New Product Portfolio21 27 48 28 76 45 121 58 79 137 106 243 123 366 ****
Total In-Line Products and New Product Portfolio2,988 3,215 6,203 3,229 9,432 3,330 12,762 3,154 3,183 6,337 2,965 9,302 3,179 12,481 (5)%(2)%
Recent LOE Products(b)
Revlimid986 1,038 2,024 1,044 3,068 1,058 4,126 759 371 1,130 250 1,380 239 1,619 (77)%(61)%
Abraxane89 62 151 55 206 77 283 41 65 106 62 168 63 231 (18)%(18)%
Total Recent LOE Products1,075 1,100 2,175 1,099 3,274 1,135 4,409 800 436 1,236 312 1,548 302 1,850 (73)%(58)%
Total$4,063 $4,315 $8,378 $4,328 $12,706 $4,465 $17,171 $3,954 $3,619 $7,573 $3,277 $10,850 $3,481 $14,331 (22)%(17)%
**    In excess of +/- 100%.
(a)    Includes OTC products, royalty revenue and other mature products.
(b)    Recent LOE products include products with significant expected decline in revenue from a prior reporting period as a result of a loss of market exclusivity.

7


BRISTOL-MYERS SQUIBB COMPANY
INTERNATIONAL REVENUES
FOREIGN EXCHANGE IMPACT (%)
(Unaudited)

Three Months Ended December 31, 2022Twelve Months Ended December 31, 2022
Revenue Change %Favorable/ (Unfavorable) FX Impact % *Revenue Change % Excluding FXRevenue Change %Favorable/ (Unfavorable) FX Impact % *Revenue Change % Excluding FX
In-Line Products
Eliquis(17)%(11)%(6)%(7)%(11)%4%
Opdivo10%(10)%20%3%(11)%14%
Pomalyst/Imnovid(7)%(11)%4%(2)%(10)%8%
Orencia(11)%(13)%2%(8)%(11)%3%
Sprycel(22)%(12)%(10)%(19)%(11)%(8)%
Yervoy4%(13)%17%9%(12)%21%
Empliciti(13)%(13)%(17)%(12)%(5)%
Mature and other products(a)
(8)%(8)%(10)%(5)%(5)%
Total In-Line Products(7)%(11)%4%(4)%(10)%6%
New Product Portfolio
Reblozyl100%(14)%**91%(18)%**
Abecma************
Zeposia50%(14)%64%******
Breyanzi************
Onureg************
Inrebic100%100%******
Total New Product Portfolio************
Total In-Line Products and New Product Portfolio(5)%(12)%7%(2)%(10)%8%
Recent LOE Products(b)
Revlimid(77)%(2)%(75)%(61)%(4)%(57)%
Abraxane(18)%(8)%(10)%(18)%(5)%(13)%
Total Recent LOE Products(73)%(3)%(70)%(58)%(3)%(55)%
Total (22)%(9)%(13)%(17)%(9)%(8)%
*    Foreign exchange impacts were derived by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.
**    In excess of +/- 100%.
(a)    Includes over-the-counter (OTC) products, royalty revenue and other mature products.
(b)    Recent LOE products include products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.

8


BRISTOL-MYERS SQUIBB COMPANY
SPECIFIED ITEMS
(Unaudited, dollars in millions)
 
2021(a)
2022
1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear
Inventory purchase price accounting adjustments$79 $88 $167 $97 $264 $ $264 $52 $102 $154 $86 $240 $53 $293 
Intangible asset impairment315 — 315 — 315  315 — — — — —   
Site exit and other costs23 24 — 24  24 — 43 43 — 43 20 63 
Cost of products sold417 89 506 97 603  603 52 145 197 86 283 73 356 
Employee compensation charges— —  1 — — — 73 73  73 
Site exit and other costs(1)— (1)— 2 2 —  6 
Marketing, selling and administrative(1)— 2 3 73 79  79 
IPRD impairments— 230 230 610 840  840 40 — 40 58 98  98 
Inventory purchase price accounting adjustments— — —  1 87 21 108 22 130  130 
Employee compensation charges— —  1 — — — 80 80  80 
Site exit and other costs— — —  1 — — — — —   
Research and development230 231 612 843  843 127 21 148 160 308  308 
Amortization of acquired intangible assets2,513 2,547 5,060 2,546 7,606 2,417 10,023 2,417 2,417 4,834 2,418 7,252 2,343 9,595 
Interest expense(b)
(34)(28)(62)(29)(91)(29)(120)(27)(21)(48)(18)(66)(17)(83)
Equity investment (income)/losses(608)(154)(762)(465)(1,227)469 (758)643 307 950 12 962 (163)799 
Integration expenses141 152 293 141 434 130 564 105 124 229 114 343 97 440 
Loss/(gain) on debt redemption281 — 281 — 281  281 275 (9)266 — 266  266 
Divestiture (gains)/losses— (11)(11)(9) (9)(211)— (211)— (211) (211)
Litigation and other settlements— — — — —   (40)— (40)36 (4)144 140 
Provision for restructuring45 78 123 27 150 19 169 23 20 43 17 60 15 75 
Contingent consideration(510)— (510)— (510)(32)(542)— — — — —   
Other— — — — —   — 42 42 28 70 1 71 
Other (income)/expense, net(685)37 (648)(324)(972)557 (415)768 463 1,231 189 1,420 77 1,497 
Increase to pretax income2,245 2,904 5,149 2,932 8,081 2,976 11,057 3,366 3,050 6,416 2,926 9,342 2,493 11,835 
Income taxes on items above(303)(292)(595)(137)(732)(261)(993)(398)(321)(719)(268)(987)(345)(1,332)
Income tax reserve release attributed to Mead Johnson— — — — —   — — — — — (225)(225)
Income taxes attributed to internal transfers of certain assets— — — — — (983)(983)— — — — — (72)(72)
Income taxes(303)(292)(595)(137)(732)(1,244)(1,976)(398)(321)(719)(268)(987)(642)(1,629)
Increase to net earnings$1,942 $2,612 $4,554 $2,795 $7,349 $1,732 $9,081 $2,968 $2,729 $5,697 $2,658 $8,355 $1,851 $10,206 
(a)    Revised to exclude significant R&D charges or other income resulting from up-front and contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights (including related income tax impacts).
(b)    Includes amortization of purchase price adjustments to Celgene debt.

9


BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF CERTAIN GAAP LINE ITEMS TO CERTAIN NON-GAAP LINE ITEMS
(Unaudited, dollars in millions)
 
2021
2022
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear
Gross Profit$8,232 $9,251 $17,483 $9,333 $26,816 $9,629 $36,445 $9,177 $9,167 $18,344 $8,865 $27,209 $8,813 $36,022 
Specified items(a)
417 89 506 97 603  603 52 145 197 86 283 73 356 
Gross profit excluding specified items8,649 9,340 17,989 9,430 27,419 9,629 37,048 9,229 9,312 18,541 8,951 27,492 8,886 36,378 
Marketing, selling and administrative1,666 1,882 3,548 1,788 5,336 2,354 7,690 1,831 1,787 3,618 1,930 5,548 2,266 7,814 
Specified items(a)
(1)— (1)(1)(2)(3)(2)(4)(6)(73)(79) (79)
Marketing, selling and administrative excluding specified items1,667 1,881 3,548 1,787 5,335 2,352 7,687 1,829 1,783 3,612 1,857 5,469 2,266 7,735 
Research and development2,219 2,478 4,697 2,980 7,677 2,518 10,195 2,260 2,321 4,581 2,418 6,999 2,510 9,509 
Specified items(a)
(1)(230)(231)(612)(843) (843)(127)(21)(148)(160)(308) (308)
Research and development excluding specified items2,218 2,248 4,466 2,368 6,834 2,518 9,352 2,133 2,300 4,433 2,258 6,691 2,510 9,201 
Amortization of acquired intangible assets2,513 2,547 5,060 2,546 7,606 2,417 10,023 2,417 2,417 4,834 2,418 7,252 2,343 9,595 
Specified items(a)
(2,513)(2,547)(5,060)(2,546)(7,606)(2,417)(10,023)(2,417)(2,417)(4,834)(2,418)(7,252)(2,343)(9,595)
Amortization of acquired intangible assets excluding specified items— — — — —   — — — — —   
Other (income)/expense, net(702)(2)(704)(409)(1,113)393 (720)649 284 933 (140)793 (217)576 
Specified items(a)
685 (37)648 324 972 (557)415 (768)(463)(1,231)(189)(1,420)(77)(1,497)
Other (income)/expense, net excluding specified items(17)(39)(56)(85)(141)(164)(305)(119)(179)(298)(329)(627)(294)(921)
(a)    Refer to the Specified Items schedule for further details. For a description of Non-GAAP financial information, see Bristol Myers Squibb "Use of non-GAAP Financial Information" herein.

10


BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF GAAP TO NON-GAAP EPS
(Unaudited, dollars and shares in millions except per share data)
 
2021
2022
 1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear1st Qtr2nd Qtr6 Months3rd Qtr9 Months4th QtrYear
Earnings before income taxes$2,530 $1,553 $4,083 $2,157 $6,240 $1,858 $8,098 $1,687 $1,958 $3,645 $2,209 $5,854 $1,859 $7,713 
Specified items(a)
2,245 2,904 5,149 2,932 8,081 2,976 11,057 3,366 3,050 6,416 2,926 9,342 2,493 11,835 
Earnings before income taxes excluding specified items4,775 4,457 9,232 5,089 14,321 4,834 19,155 5,053 5,008 10,061 5,135 15,196 4,352 19,548 
Provision/(benefit) for income taxes501 492 993 605 1,598 (514)1,084 404 529 933 601 1,534 (166)1,368 
Income taxes on specified items(a)
303 292 595 137 732 261 993 398 321 719 268 987 345 1,332 
Income tax reserve release attributed to Mead Johnson(a)
— — — — —   — — — — — 225 225 
Income taxes attributed to internal transfer of certain assets(a)
— — — — — 983 983 — — — — — 72 72 
Provision for income taxes excluding tax on specified items, income tax reserve release attributed to Mead Johnson and income taxes attributed to internal transfer of certain assets804 784 1,588 742 2,330 730 3,060 802 850 1,652 869 2,521 476 2,997 
Net earnings attributable to BMS used for diluted EPS calculation - GAAP2,021 1,055 3,076 1,546 4,622 2,372 6,994 1,278 1,421 2,699 1,606 4,305 2,022 6,327 
Specified items(a)
1,942 2,612 4,554 2,795 7,349 1,732 9,081 2,968 2,729 5,697 2,658 8,355 1,851 10,206 
Net earnings attributable to BMS used for diluted EPS calculation excluding specified items - non-GAAP3,963 3,667 7,630 4,341 11,971 4,104 16,075 4,246 4,150 8,396 4,264 12,660 3,873 16,533 
Weighted-average common shares outstanding - diluted-GAAP2,265 2,252 2,258 2,243 2,253 2,219 2,245 2,164 2,149 2,157 2,148 2,154 2,124 2,146 
Weighted-average common shares outstanding - diluted-non-GAAP2,265 2,252 2,258 2,243 2,253 2,219 2,245 2,164 2,149 2,157 2,148 2,154 2,124 2,146 
Diluted earnings per share - GAAP*$0.89 $0.47 $1.36 $0.69 $2.05 $1.07 $3.12 $0.59 $0.66 $1.25 $0.75 $2.00 $0.95 $2.95 
Diluted earnings per share attributable to specified items(a)
0.85 1.16 2.02 1.24 3.26 0.77 4.04 1.37 1.27 2.64 1.24 3.88 0.87 4.75 
Diluted earnings per share - non-GAAP*$1.74 $1.63 $3.38 $1.93 $5.31 $1.84 $7.16 $1.96 $1.93 $3.89 $1.99 $5.88 $1.82 $7.70 
Effective tax rate19.8 %31.7 %24.3 %28.0 %25.6 %(27.7)%13.4 %23.9 %27.0 %25.6 %27.2 %26.2 %(8.9)%17.7 %
Specified items(a)
(3.0)%(14.1)%(7.1)%(13.4)%(9.3)%42.8 %2.6 %(8.0)%(10.0)%(9.2)%(10.3)%(9.6)%19.8 %(2.4)%
Effective tax rate excluding specified items16.8 %17.6 %17.2 %14.6 %16.3 %15.1 %16.0 %15.9 %17.0 %16.4 %16.9 %16.6 %10.9 %15.3 %
*    Quarterly amounts may not add to the year-to-date amounts, as each period is computed on a discrete basis.
(a)    Refer to the Specified Items schedule for further details. Effective tax rate on the Specified Items represents the difference between the GAAP and Non-GAAP effective tax rate. For a description of Non-GAAP financial information, see Bristol Myers Squibb "Use of non-GAAP Financial Information" herein.



11


BRISTOL-MYERS SQUIBB COMPANY
SELECTED BALANCE SHEET INFORMATION
(Unaudited, dollars in millions)
March 31,
2021
June 30,
2021
September 30,
2021
December 31, 2021March 31,
2022
June 30,
2022
September 30,
2022
December 31, 2022
Cash and cash equivalents$10,982 $11,024 $13,540 $13,979 $12,369 $10,750 $7,734 $9,123 
Marketable debt securities - current1,948 1,946 2,123 2,987 2,599 2,478 1,293 130 
Marketable debt securities - non-current288 143 46 — — — — — 
Cash, Cash Equivalents and Marketable Debt Securities13,218 13,113 15,709 16,966 14,968 13,228 9,027  9,253 
Short-term debt obligations(1,777)(2,655)(5,065)(4,948)(7,522)(4,953)(2,132)(4,264)
Long-term debt(44,505)(42,503)(39,677)(39,605)(37,450)(37,107)(36,966)(35,056)
Net Debt Position$(33,064)$(32,045)$(29,033)$(27,587)$(30,004)$(28,832)$(30,071) $(30,067)




12


BRISTOL-MYERS SQUIBB COMPANY
2023 FULL YEAR PROJECTED DILUTED EPS FROM OPERATIONS
EXCLUDING PROJECTED SPECIFIED ITEMS
Full Year 2023
Pre-taxTaxAfter-tax
Projected Diluted Earnings Attributable to Shareholders per Common Share - GAAP$4.03 to $4.33
Projected Specified Items:
Purchase price accounting adjustments(a)
4.26 0.44 3.82 
Acquisition, restructuring and integration expenses(b)
0.13 0.03 0.10 
Total4.39 0.47 3.92 
Projected Diluted Earnings Attributable to Shareholders per Common Share - Non-GAAP$7.95 to $8.25
(a)    Includes amortization of acquired intangible assets, unwind of inventory purchase price adjustments and amortization of fair value adjustments of debt assumed from Celgene.
(b)    Includes acquisition-related restructuring and integration expenses recognized primarily in Other (income)/expense, net.

The following table summarizes the company's 2023 financial guidance:
Line itemGAAPNon-GAAP
Total reported revenues~ 2% increase~ 2% increase
Total revenues Ex-FX(c)
~ 2% increase~ 2% increase
Revlimid~ $6.5 billion~ $6.5 billion
Gross margin~ 77%~ 77%
Operating expenses(d)
Mid single-digit declineLow single-digit decline
Effective tax rate~ 22%~ 17%
(c)    Ex-FX excludes the impact of foreign exchange calculated by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our prior-period results.
(d)    Operating expenses consist of Marketing, selling and administrative expenses and Research and development expenses, excluding Acquired IPRD expenses.
The GAAP financial results for the full year of 2023 will include specified items, including purchase price accounting adjustments, acquisition and integration expenses, charges associated with restructuring, downsizing and streamlining worldwide operations, impairment of intangible assets, loss on debt redemption, divestiture gains or losses and equity investment (including fair value adjustments attributed to limited partnership equity method investments) and Turning Point related charges, among other items. The 2023 financial guidance excludes the impact of any potential future strategic acquisitions and divestitures and any specified items that have not yet been identified and quantified. For a fuller discussion of items that could impact full year GAAP results, as well as the use of non-GAAP financial information, see Bristol Myers Squibb Reports Fourth Quarter and Full Year Financial Results for 2022 on February 2, 2023, including “2023 Financial Guidance” and “Use of non-GAAP Financial Information” therein.
13


BRISTOL-MYERS SQUIBB COMPANY
USE OF NON-GAAP FINANCIAL INFORMATION

In discussing financial results and guidance, the company refers to financial measures that are not in accordance with U.S. Generally Accepted Accounting Principles (GAAP). The non-GAAP financial measures are provided as supplemental information to the financial measures presented in this supplementary information to the earnings release that are calculated and presented in accordance with GAAP and are presented because management has evaluated the company’s financial results both including and excluding the adjusted items or the effects of foreign currency translation, as applicable, and believes that the non-GAAP financial measures presented portray the results of the company’s baseline performance, supplement or enhance management, analysts and investors overall understanding of the company’s underlying financial performance and trends and facilitate comparisons among current, past and future periods. In addition, non-GAAP gross margin, which is gross profit excluding certain specified items as a percentage of revenues, non-GAAP operating margin, which is gross profit less marketing, selling and administrative expense and research and development expense excluding certain specified items as a percentage of revenues, non-GAAP operating expenses, which is marketing, selling and administrative and research and development expenses excluding certain specified items, non-GAAP marketing, selling and administrative expenses, which is marketing, selling and administrative expense excluding certain specified items, and non-GAAP research and development expenses, which is research and development expenses excluding certain specified items, are relevant and useful for investors because they allow investors to view performance in a manner similar to the method used by our management and make it easier for investors, analysts and peers to compare our operating performance to other companies in our industry and to compare our year-over-year results.

This supplementary information to the earnings release also provides certain revenues and expenses as well as non-GAAP measures excluding the impact of foreign exchange (“Ex-Fx”). We calculate foreign exchange impacts by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results. Ex-Fx financial measures are not accounted for according to GAAP because they remove the effects of currency movements from GAAP results.

Non-GAAP financial measures such as non-GAAP earnings and related EPS information, are adjusted to exclude certain costs, expenses, gains and losses and other specified items that are evaluated on an individual basis after considering their quantitative and qualitative aspects and typically have one or more of the following characteristics, such as being highly variable, difficult to project, unusual in nature, significant to the results of a particular period or not indicative of past or future operating results. These items are excluded from non-GAAP earnings and related EPS information because the company believes they neither relate to the ordinary course of the company’s business nor reflect the company’s underlying business performance. Similar charges or gains were recognized in prior periods and will likely reoccur in future periods, including amortization of acquired intangible assets, including product rights that generate a significant portion of our ongoing revenue and will recur until the intangible assets are fully amortized, unwind of inventory purchase price adjustments, acquisition and integration expenses, restructuring costs, accelerated depreciation and impairment of property, plant and equipment and intangible assets, divestiture gains or losses, stock compensation resulting from acquisition-related equity awards, pension, legal and other contractual settlement charges, equity investment and contingent value rights fair value adjustments (including fair value adjustments attributed to limited partnership equity method investments) and amortization of fair value adjustments of debt acquired from Celgene in our 2019 exchange offer, among other items. Certain other significant tax items are also excluded such as the impact resulting from the release of income tax reserves related to the Mead Johnson split-off transaction, internal transfers of certain assets to streamline our legal entity structure subsequent to the Celgene acquisition. Deferred and current income taxes attributed to these items are also adjusted for considering their individual impact to the overall tax expense, deductibility and jurisdictional tax rates.

Beginning with the first quarter of 2022, significant R&D charges or other income resulting from upfront or contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights are no longer excluded from our non-GAAP financial measures. We made these changes to our presentation of non-GAAP financial measures following comments from and discussions with the U.S. Securities and Exchange Commission. For purposes of comparability, the non-GAAP financial measures for the prior periods have been updated to reflect this change.

Because the non-GAAP financial measures are not calculated in accordance with GAAP, they should not be considered superior to and are not intended to be considered in isolation or as a substitute for the related financial measures presented in the press release that are prepared in accordance with GAAP and may not be the same as or comparable to similarly titled measures presented by other companies due to possible differences in method and in the items being adjusted. We encourage investors to review our financial statements and publicly filed reports in their entirety and not to rely on any single financial measure.

Reconciliations of the non-GAAP financial measures to the most comparable GAAP measures are provided in the accompanying financial tables and will also be available on the company's website at www.bms.com Within the accompanying financial tables presented, certain columns and rows may not add due to the use of rounded numbers. Percentages and earnings per share amounts presented are calculated from the underlying amounts.

Also note that a reconciliation of forward-looking non-GAAP gross margin, non-GAAP operating expenses and non-GAAP tax rate is not provided because comparable GAAP measures for such measures are not reasonably accessible or reliable due to the inherent difficulty in forecasting and quantifying measures that would be necessary for such reconciliation. Namely, we are not able to reliably predict the impact of the unwind of inventory purchase price adjustments, accelerated depreciation and impairment of property, plant and equipment and intangible assets, and stock
14


compensation resulting from acquisition-related equity awards, or currency exchange rates beyond the next twelve months. In addition, the company believes such a reconciliation would imply a degree of precision and certainty that could be confusing to investors. The variability of the specified items may have a significant and unpredictable impact on our future GAAP results.
15