Calculation of Filing Fee Tables
Form S-8
(Form Type)
Krystal Biotech, Inc.
(Exact Name of Registrant as Specified in its Charter)
Table 1: Newly Registered Securities
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| Security Type | Security Class Title | Fee Calculation Rule | Amount Registered (1) | Proposed Maximum Offering Price Per Unit | Maximum Aggregate Offering Price | Fee Rate | Amount of Registration Fee |
| Fees to Be Paid | Equity | Common Stock, $0.00001 par value per share | 457(c) and 457 (h) | 1,027,885(2) | $82.04(3) | $84,327,685.40 | 0.0001102 | $9,292.91 |
| Total Offering Amounts | | $84,327,685.40 | | $9,292.91 |
| Total Fee Offsets | | | | — |
| Net Fee Due | | | | $9,292.91 |
(1) Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall also cover any additional shares of common stock that become issuable under Krystal Biotech, Inc. (the “Registrant”)’s 2017 IPO Stock Incentive Plan (the “Plan”), by reason of certain corporate transactions or events, including any share dividend, share split, recapitalization or certain other transactions that result in an increase in the number of the outstanding shares of the common stock.
(2) Represents shares of common stock that were added to the shares reserved for future issuance under the Plan pursuant to the “evergreen” provision of the Plan, which was originally approved by the Registrant’s stockholders on September 5, 2017.
(3) Estimated in accordance with Rules 457(c) and (h) under the Securities Act solely for the purpose of calculating the registration fee on the basis of $82.04 per share, which represents the average of the high and low sales prices of the Registrant’s common stock as reported on the Nasdaq Capital Market on February 1, 2023.