The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS IN COM 004225108 1,590,000 100,000 SH SOLE 100,000 0 0
ADICET BIO INC COM COM 007002108 1,379,995 154,708 SH SOLE 154,708 0 0
ALBIREO PHARMA INC COM COM 01345P106 820,420 38,000 SH SOLE 38,000 0 0
ALKERMES PLC SHS SHS G01767105 15,483,230 593,000 SH SOLE 593,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 314,000 50,000 SH SOLE 50,000 0 0
ALNYLAM PHARMACEUTICALS I COM 02043Q107 9,018,160 38,000 SH SOLE 38,000 0 0
AMGEN INC COM COM 031162100 4,265,225 16,246 SH SOLE 16,246 0 0
APELLIS PHARMACEUTICALS I COM 03753U106 1,638,256 31,700 SH SOLE 31,700 0 0
ARVINAS INC COM COM 04335A105 580,550 17,000 SH SOLE 17,000 0 0
ASCENDIS PHARMA A/S SPONS Sponsored ADR 04351P101 3,588,270 29,400 SH SOLE 29,400 0 0
ASTRAZENECA PLC SPONSORED SPONSORED ADR 046353108 4,406,350 65,000 SH SOLE 65,000 0 0
AURINIA PHARMACEUTICALS I COM 05156V102 2,477,650 573,530 SH SOLE 573,530 0 0
BEAM THERAPEUTICS INC COM COM 07373V105 919,085 23,500 SH SOLE 23,500 0 0
BEIGENE LTD SPONSORED ADR Sponsored ADR 07725L102 3,452,116 15,700 SH SOLE 15,700 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 653,790 57,000 SH SOLE 57,000 0 0
BIOGEN INC COMMON STOCK COM 09062X103 5,923,520 21,400 SH SOLE 21,400 0 0
BIOMARIN PHARMACEUTICAL I COM 09061G101 4,514,467 43,656 SH SOLE 43,656 0 0
BLACK DIAMOND THERAPEUTIC COM 0920E3105 79,200 44,000 SH SOLE 44,000 0 0
CARIBOU BIOSCIENCES INC C COM 142038108 1,619,562 257,892 SH SOLE 257,892 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 8,914,788 340,389 SH SOLE 340,389 0 0
CONCERT PHARMACEUTICALS I COM 206022105 1,172,672 200,800 SH SOLE 200,800 0 0
CRISPR THERAPEUTICS AG CO NAMEN AKT H17182108 1,390,230 34,200 SH SOLE 34,200 0 0
DENALI THERAPEUTICS INC C COM 24823R105 1,056,020 38,000 SH SOLE 38,000 0 0
DYNE THERAPEUTICS INC COM COM 26818M108 7,417,157 641,068 SH SOLE 641,068 0 0
EXELIXIS INC COM COM 30161Q104 8,709,720 543,000 SH SOLE 543,000 0 0
FATE THERAPEUTICS INC COM COM 31189P102 463,680 46,000 SH SOLE 46,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 1,408,497 193,741 SH SOLE 193,741 0 0
GILEAD SCIENCES INC COMMO COM 375558103 4,942,435 57,584 SH SOLE 57,584 0 0
GUARDANT HEALTH INC COM COM 40131M109 2,024,165 74,500 SH SOLE 74,500 0 0
Harmony Biosciences Holdi COM 413197104 14,560,725 264,500 SH SOLE 264,500 0 0
HORIZON THERAPEUTICS PLC SHS G4617B105 35,828,179 314,973 SH SOLE 314,973 0 0
HUTCHMED CHINA LIMITED SP SPONSORED ADS 44842L103 1,003,000 68,000 SH SOLE 68,000 0 0
IDEAYA BIOSCIENCES INC CO COM 45166A102 1,980,530 109,000 SH SOLE 109,000 0 0
ILLUMINA INC COM COM 452327109 9,396,720 46,500 SH SOLE 46,500 0 0
I-MAB SPONSORED ADS SPONSORED ADS 44975P103 1,291,676 310,499 SH SOLE 310,499 0 0
INCYTE CORP INC COM COM 45337C102 18,390,990 229,000 SH SOLE 229,000 0 0
INSMED INC COM PAR $.01 COM 457669307 800,396 40,100 SH SOLE 40,100 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 836,640 24,000 SH SOLE 24,000 0 0
INTRA-CELLULAR THERAPIES COM 46116X101 11,733,964 221,856 SH SOLE 221,856 0 0
IOVANCE BIOTHERAPEUTICS I COM 462260100 357,280 56,000 SH SOLE 56,000 0 0
IRONWOOD PHARMACEUTICALS COM 46333X108 743,400 60,000 SH SOLE 60,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 2,739,444 17,200 SH SOLE 17,200 0 0
KRYSTAL BIOTECH INC COM COM 501147102 3,558,150 45,000 SH SOLE 45,000 0 0
Legend Biotech Corp SPONSORED ADS 52490G102 1,894,300 38,000 SH SOLE 38,000 0 0
MIRATI THERAPEUTICS INC C COM 60468T105 11,055,640 244,000 SH SOLE 244,000 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 1,312,875 67,500 SH SOLE 67,500 0 0
NOVAVAX INC COM 670002401 1,360,775 132,500 SH SOLE 132,500 0 0
Novocure Ltd ORD SHS G6674U108 2,344,000 32,000 SH SOLE 32,000 0 0
PTC THERAPEUTICS INC COM COM 69366J200 5,493,600 144,000 SH SOLE 144,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 8,080,128 11,200 SH SOLE 11,200 0 0
RELMADA THERAPEUTICS INC COM 75955J402 34,900 10,000 SH SOLE 10,000 0 0
REVANCE THERAPEUTICS INC COM 761330109 2,214,000 120,000 SH SOLE 120,000 0 0
ROCKET PHARMACEUTICALS IN COM 77313F106 1,231,020 63,000 SH SOLE 63,000 0 0
SANOFI SPONSORED ADR 80105N105 6,942,530 143,500 SH SOLE 143,500 0 0
SEAGEN INC COM COM 81181C104 21,356,700 166,200 SH SOLE 166,200 0 0
SUPERNUS PHARMACEUTICALS COM 868459108 13,671,775 383,500 SH SOLE 383,500 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 7,963,189 379,019 SH SOLE 379,019 0 0
ULTRAGENYX PHARMACEUTICAL COM 90400D108 8,060,348 174,052 SH SOLE 174,052 0 0
UNIQURE N.V. COM EUR0.05 SHS N90064101 14,297,160 631,500 SH SOLE 631,500 0 0
UNITED THERAPEUTICS CORP COM 91307C102 4,171,200 15,000 SH SOLE 15,000 0 0
VERA THERAPEUTICS CL A 92337R101 5,428,260 281,257 SH SOLE 281,257 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,003,425 25,500 SH SOLE 25,500 0 0
ZAI LAB LTD ADR ADR 98887Q104 2,423,221 78,958 SH SOLE 78,958 0 0