American Funds Insurance Series® - Target Date Series
American Funds® IS 2035 Target Date Fund
Investment portfolio
September 30, 2022
unaudited
Growth funds 29.36%   Shares Value
(000)
AMCAP Fund, Class R-61 239 $7
The Growth Fund of America, Class R-6 139 7
SMALLCAP World Fund, Inc., Class R-61 98 6
New Perspective Fund, Class R-6 113 5
American Funds Global Insight Fund, Class R-6 259 4
The New Economy Fund, Class R-61 47 2
New World Fund, Inc., Class R-6 16 1
Total growth funds (cost: $40,000)     32
Growth-and-income funds 32.11%      
American Mutual Fund, Class R-6 169 8
Capital World Growth and Income Fund, Class R-6 165 8
Fundamental Investors, Class R-6 125 7
Washington Mutual Investors Fund, Class R-6 125 6
The Investment Company of America, Class R-6 113 4
International Growth and Income Fund, Class R-6 77 2
Total growth-and-income funds (cost: $39,000)     35
Equity-income funds 7.34%      
Capital Income Builder, Class R-6 67 4
The Income Fund of America, Class R-6 204 4
Total equity-income funds (cost: $9,000)     8
Balanced funds 12.84%      
American Balanced Fund, Class R-6 326 9
American Funds Global Balanced Fund, Class R-6 184 5
Total balanced funds (cost: $17,000)     14
Fixed income funds 18.35%      
U.S. Government Securities Fund, Class R-6 458 6
American Funds Inflation Linked Bond Fund, Class R-6 472 4
American Funds Mortgage Fund, Class R-6 346 3
American Funds Multi-Sector Income Fund, Class R-6 329 3
Intermediate Bond Fund of America, Class R-6 153 2
American Funds Insurance Series — Target Date Series — Page 1 of 15

unaudited
Fixed income funds (continued)   Shares Value
(000)
American Funds Strategic Bond Fund, Class R-6 127 $1
Capital World Bond Fund, Class R-6 79 1
Total fixed income funds (cost: $23,000)     20
Total investment securities 100.00% (cost: $128,000)     109
Other assets less liabilities 0.00%     2
Net assets 100.00%     $109
Investments in affiliates3

  Value of
affiliates at
1/1/2022
(000)
Additions
(000)
Reductions
(000)
Net
realized
(loss) gain
(000)
  Net
unrealized
depreciation
(000)
  Value of
affiliates at
9/30/2022
(000)
  Dividend
income
(000)
  Capital gain
distributions
received
(000)
Growth funds 29.36%
AMCAP Fund, Class R-61 $10 $1 $—2 $2   $(4)   $7   $—   $—2
The Growth Fund of America, Class R-6 10 2 2 2   (3)   7    
SMALLCAP World Fund, Inc., Class R-61 7 2 2 2   (3)   6    
New Perspective Fund, Class R-6 8 2 1 2   (2)   5    
American Funds Global Insight Fund, Class R-6 5 2 2 2   (1)   4    
The New Economy Fund, Class R-61 4 1 2   (1)   2    
New World Fund, Inc., Class R-6 2 1 2   2   1    
                32        
Growth-and-income funds 32.11%
American Mutual Fund, Class R-6 10 2 1 2   (1)   8   2  
Capital World Growth and Income Fund, Class R-6 10 1   (3)   8   2  
Fundamental Investors, Class R-6 10 2 1 2   (2)   7   2   2
Washington Mutual Investors Fund, Class R-6 8 1 1 2   (2)   6   2   2
The Investment Company of America, Class R-6 6 2 1 2   (1)   4   2   2
International Growth and Income Fund, Class R-6 3 2 2 2   (1)   2   2  
                35        
Equity-income funds 7.34%
Capital Income Builder, Class R-6 5 2 2 2   (1)   4   2  
The Income Fund of America, Class R-6 6 2 1 2   (1)   4   2  
                8        
Balanced funds 12.84%
American Balanced Fund, Class R-6 11 1 1 2   (2)   9   2   2
American Funds Global Balanced Fund, Class R-6 7 2 2 2   (2)   5   2  
                14        
Fixed income funds 18.35%
U.S. Government Securities Fund, Class R-6 10 1 3 (1)   (1)   6   2  
American Funds Inflation Linked Bond Fund, Class R-6 4 1 2 2   (1)   4    
American Funds Mortgage Fund, Class R-6 2 1 2 2   2   3   2  
American Funds Multi-Sector Income Fund, Class R-6 3 2 2   2   3   2  
Intermediate Bond Fund of America, Class R-6 2 1 1 2   2   2   2  
American Funds Strategic Bond Fund, Class R-6 1   2   1   2  
Capital World Bond Fund, Class R-6 2 1 2 2   2   1   2  
                20        
Total 100.00%       $(1)   $(32)   $109   $—2   $—2
American Funds Insurance Series — Target Date Series — Page 2 of 15

unaudited
1 Fund did not produce income during the last 12 months.
2 Amount less than one thousand.
3 Part of the same “group of investment companies“ as the fund as defined under the Investment Company Act of 1940, as amended.
American Funds Insurance Series — Target Date Series — Page 3 of 15

American Funds® IS 2030 Target Date Fund
Investment portfolio
September 30, 2022
unaudited
Growth funds 19.39%   Shares Value
(000)
AMCAP Fund, Class R-61 595 $17
The Growth Fund of America, Class R-6 282 14
American Funds Global Insight Fund, Class R-6 603 10
SMALLCAP World Fund, Inc., Class R-61 157 9
New Perspective Fund, Class R-6 155 7
Total growth funds (cost: $73,000)     57
Growth-and-income funds 28.57%      
American Mutual Fund, Class R-6 453 20
Capital World Growth and Income Fund, Class R-6 443 20
Washington Mutual Investors Fund, Class R-6 307 15
Fundamental Investors, Class R-6 227 13
The Investment Company of America, Class R-6 261 10
International Growth and Income Fund, Class R-6 207 6
Total growth-and-income funds (cost: $96,000)     84
Equity-income funds 7.82%      
The Income Fund of America, Class R-6 546 12
Capital Income Builder, Class R-6 203 11
Total equity-income funds (cost: $26,000)     23
Balanced funds 12.93%      
American Balanced Fund, Class R-6 879 23
American Funds Global Balanced Fund, Class R-6 496 15
Total balanced funds (cost: $45,000)     38
Fixed income funds 31.29%      
American Funds Inflation Linked Bond Fund, Class R-6 1,724 16
American Funds Mortgage Fund, Class R-6 1,698 15
U.S. Government Securities Fund, Class R-6 1,240 15
Intermediate Bond Fund of America, Class R-6 1,017 13
The Bond Fund of America, Class R-6 1,036 12
American Funds Multi-Sector Income Fund, Class R-6 1,050 9
American Funds Strategic Bond Fund, Class R-6 622 6
Capital World Bond Fund, Class R-6 386 6
Total fixed income funds (cost: $104,000)     92
Total investment securities 100.00% (cost: $344,000)     294
Other assets less liabilities 0.00%     2
Net assets 100.00%     $294
American Funds Insurance Series — Target Date Series — Page 4 of 15

unaudited
Investments in affiliates3

  Value of
affiliates at
1/1/2022
(000)
Additions
(000)
Reductions
(000)
Net
realized
loss
(000)
  Net
unrealized
depreciation
(000)
  Value of
affiliates at
9/30/2022
(000)
  Dividend
income
(000)
  Capital gain
distributions
received
(000)
Growth funds 19.39%
AMCAP Fund, Class R-61 $17 $9 $1 $2   $(8)   $17   $—   $1
The Growth Fund of America, Class R-6 14 6 1 2   (5)   14    
American Funds Global Insight Fund, Class R-6 10 4 1 2   (3)   10    
SMALLCAP World Fund, Inc., Class R-61 9 4 1 2   (3)   9    
New Perspective Fund, Class R-6 7 3 2 2   (3)   7    
                57        
Growth-and-income funds 28.57%
American Mutual Fund, Class R-6 20 6 2 (1)   (3)   20   2  
Capital World Growth and Income Fund, Class R-6 19 8 1 2   (6)   20   2  
Washington Mutual Investors Fund, Class R-6 14 5 2 2   (4)   15   2   2
Fundamental Investors, Class R-6 13 5 1 2   (4)   13   2   2
The Investment Company of America, Class R-6 10 4 1 2   (3)   10   2   2
International Growth and Income Fund, Class R-6 6 2 2 2   (2)   6   2  
                84        
Equity-income funds 7.82%
Capital Income Builder, Class R-6 11 4 1 2   (2)   12   2  
The Income Fund of America, Class R-6 11 3 1 2   (2)   11   2  
                23        
Balanced funds 12.93%
American Balanced Fund, Class R-6 22 7 1 2   (5)   23   2   2
American Funds Global Balanced Fund, Class R-6 14 5 2 2   (4)   15   2  
                38        
Fixed income funds 31.29%
American Funds Inflation Linked Bond Fund, Class R-6 12 6 2 2   (2)   16    
American Funds Mortgage Fund, Class R-6 14 4 1 2   (2)   15   2  
U.S. Government Securities Fund, Class R-6 18 6 6 (1)   (2)   15   2  
Intermediate Bond Fund of America, Class R-6 16 6 8 2   (1)   13   2  
The Bond Fund of America, Class R-6 6 7   (1)   12   2   2
American Funds Multi-Sector Income Fund, Class R-6 9   2   9   2  
American Funds Strategic Bond Fund, Class R-6 6   2   6   2  
Capital World Bond Fund, Class R-6 14 5 10 (3)   2   6   2  
                92        
Total 100.00%       $(5)   $(65)   $294   $—2   $1
1 Fund did not produce income during the last 12 months.
2 Amount less than one thousand.
3 Part of the same “group of investment companies“ as the fund as defined under the Investment Company Act of 1940, as amended.
American Funds Insurance Series — Target Date Series — Page 5 of 15

American Funds® IS 2025 Target Date Fund
Investment portfolio
September 30, 2022
unaudited
Growth funds 10.71%   Shares Value
(000)
AMCAP Fund, Class R-61 1,860 $54
American Funds Global Insight Fund, Class R-6 2,270 37
The Growth Fund of America, Class R-6 456 23
SMALLCAP World Fund, Inc., Class R-61 211 12
New Perspective Fund, Class R-6 247 11
Total growth funds (cost: $173,000)     137
Growth-and-income funds 24.94%      
American Mutual Fund, Class R-6 1,810 81
Capital World Growth and Income Fund, Class R-6 1,764 81
Washington Mutual Investors Fund, Class R-6 1,332 63
Fundamental Investors, Class R-6 679 38
The Investment Company of America, Class R-6 983 38
International Growth and Income Fund, Class R-6 650 18
Total growth-and-income funds (cost: $363,000)     319
Equity-income funds 10.71%      
The Income Fund of America, Class R-6 3,675 79
Capital Income Builder, Class R-6 1,006 58
Total equity-income funds (cost: $152,000)     137
Balanced funds 12.43%      
American Balanced Fund, Class R-6 3,811 102
American Funds Global Balanced Fund, Class R-6 1,913 57
Total balanced funds (cost: $186,000)     159
Fixed income funds 41.29%      
The Bond Fund of America, Class R-6 8,802 99
American Funds Inflation Linked Bond Fund, Class R-6 9,553 91
Intermediate Bond Fund of America, Class R-6 5,964 73
American Funds Mortgage Fund, Class R-6 8,161 72
U.S. Government Securities Fund, Class R-6 5,367 65
American Funds Multi-Sector Income Fund, Class R-6 5,381 47
American Funds Strategic Bond Fund, Class R-6 3,434 33
American Funds Insurance Series — Target Date Series — Page 6 of 15

unaudited
Fixed income funds (continued)   Shares Value
(000)
Capital World Bond Fund, Class R-6 1,673 $26
American High-Income Trust, Class R-6 2,497 22
Total fixed income funds (cost: $600,000)     528
Total investment securities 100.08% (cost: $1,474,000)     1,280
Other assets less liabilities (0.08)%     (1)
Net assets 100.00%     $1,279
Investments in affiliates2

  Value of
affiliates at
1/1/2022
(000)
Additions
(000)
Reductions
(000)
Net
realized
loss
(000)
  Net
unrealized
depreciation
(000)
  Value of
affiliates at
9/30/2022
(000)
  Dividend
income
(000)
  Capital gain
distributions
received
(000)
Growth funds 10.71%
AMCAP Fund, Class R-61 $57 $29 $6 $(2)   $(24)   $54   $  $4
American Funds Global Insight Fund, Class R-6 35 15 2 3   (11)   37    
The Growth Fund of America, Class R-6 29 10 6 (2)   (8)   23    
SMALLCAP World Fund, Inc., Class R-61 14 5 3 3   (4)   12    
New Perspective Fund, Class R-6 15 4 3 (1)   (4)   11    
                137        
Growth-and-income funds 24.94%
American Mutual Fund, Class R-6 77 29 10 (1)   (14)   81   1  
Capital World Growth and Income Fund, Class R-6 77 37 7 (1)   (25)   81   1  
Washington Mutual Investors Fund, Class R-6 59 24 4 3   (16)   63   1   2
Fundamental Investors, Class R-6 36 16 3 3   (11)   38   3   1
The Investment Company of America, Class R-6 36 15 2 3   (11)   38   1   1
International Growth and Income Fund, Class R-6 19 8 2 (1)   (6)   18   1  
                319        
Equity-income funds 10.71%
The Income Fund of America, Class R-6 64 31 2 3   (14)   79   2  
Capital Income Builder, Class R-6 51 20 2 3   (11)   58   1  
                137        
Balanced funds 12.43%
American Balanced Fund, Class R-6 94 36 6 3   (22)   102   1   1
American Funds Global Balanced Fund, Class R-6 53 21 2 3   (15)   57   1  
                159        
Fixed income funds 41.29%
The Bond Fund of America, Class R-6 68 46   (15)   99   2   3
American Funds Inflation Linked Bond Fund, Class R-6 64 40 3 3   (13)   91    
Intermediate Bond Fund of America, Class R-6 100 40 56 (5)   (6)   73   2  
American Funds Mortgage Fund, Class R-6 60 25 3 3   (10)   72   1  
U.S. Government Securities Fund, Class R-6 63 24 11 (2)   (9)   65   2  
American Funds Multi-Sector Income Fund, Class R-6 49   (2)   47   1  
American Funds Strategic Bond Fund, Class R-6 35   (2)   33   3  
Capital World Bond Fund, Class R-6 54 27 42 (10)   (3)   26   1  
American High-Income Trust, Class R-6 20 16 10 (1)   (3)   22   1  
                528        
Total 100.08%       $(26)   $(259)   $1,280   $20   $9
American Funds Insurance Series — Target Date Series — Page 7 of 15

unaudited
1 Fund did not produce income during the last 12 months.
2 Part of the same “group of investment companies“ as the fund as defined under the Investment Company Act of 1940, as amended.
3 Amount less than one thousand.
American Funds Insurance Series — Target Date Series — Page 8 of 15

American Funds® IS 2020 Target Date Fund
Investment portfolio
September 30, 2022
unaudited
Growth funds 4.16%   Shares Value
(000)
American Funds Global Insight Fund, Class R-6 3,497 $57
AMCAP Fund, Class R-61 1,505 44
Total growth funds (cost: $135,000)     101
Growth-and-income funds 22.22%      
American Mutual Fund, Class R-6 3,165 143
Capital World Growth and Income Fund, Class R-6 2,791 128
Washington Mutual Investors Fund, Class R-6 2,489 118
Fundamental Investors, Class R-6 1,261 70
The Investment Company of America, Class R-6 1,831 70
International Growth and Income Fund, Class R-6 387 11
Total growth-and-income funds (cost: $630,000)     540
Equity-income funds 15.68%      
The Income Fund of America, Class R-6 11,468 247
Capital Income Builder, Class R-6 2,338 134
Total equity-income funds (cost: $429,000)     381
Balanced funds 11.93%      
American Balanced Fund, Class R-6 7,231 194
American Funds Global Balanced Fund, Class R-6 3,245 96
Total balanced funds (cost: $353,000)     290
Fixed income funds 46.09%      
The Bond Fund of America, Class R-6 17,827 200
American Funds Inflation Linked Bond Fund, Class R-6 20,426 194
Intermediate Bond Fund of America, Class R-6 12,266 151
American Funds Mortgage Fund, Class R-6 16,915 150
U.S. Government Securities Fund, Class R-6 10,286 125
American Funds Multi-Sector Income Fund, Class R-6 11,510 101
American High-Income Trust, Class R-6 8,559 76
American Funds Strategic Bond Fund, Class R-6 7,745 74
Capital World Bond Fund, Class R-6 3,202 49
Total fixed income funds (cost: $1,291,000)     1,120
Total investment securities 100.08% (cost: $2,838,000)     2,432
Other assets less liabilities (0.08)%     (2)
Net assets 100.00%     $2,430
American Funds Insurance Series — Target Date Series — Page 9 of 15

unaudited
Investments in affiliates2

  Value of
affiliates at
1/1/2022
(000)
Additions
(000)
Reductions
(000)
Net
realized
loss
(000)
  Net
unrealized
depreciation
(000)
  Value of
affiliates at
9/30/2022
(000)
  Dividend
income
(000)
  Capital gain
distributions
received
(000)
Growth funds 4.16%
American Funds Global Insight Fund, Class R-6 $78 $2 $4 $3   $(19)   $57   $  $
AMCAP Fund, Class R-61 66 6 3 (1)   (24)   44     3
                101        
Growth-and-income funds 22.22%
American Mutual Fund, Class R-6 179 5 16 3   (25)   143   2  
Capital World Growth and Income Fund, Class R-6 167 14 6 (1)   (46)   128   2  
Washington Mutual Investors Fund, Class R-6 149 10 10 3   (31)   118   2   4
Fundamental Investors, Class R-6 89 9 3 (1)   (24)   70   1   1
The Investment Company of America, Class R-6 90 7 3 (1)   (23)   70   1   1
International Growth and Income Fund, Class R-6 18 3 2 (1)   (4)   11   3  
                540        
Equity-income funds 15.68%
The Income Fund of America, Class R-6 286 21 11 (1)   (48)   247   6  
Capital Income Builder, Class R-6 161 5 3 3   (29)   134   3  
                381        
Balanced funds 11.93%
American Balanced Fund, Class R-6 239 8 4 (1)   (48)   194   3   1
American Funds Global Balanced Fund, Class R-6 119 7 2 3   (28)   96   1  
                290        
Fixed income funds 46.09%
The Bond Fund of America, Class R-6 239 10 10 (1)   (38)   200   5   3
American Funds Inflation Linked Bond Fund, Class R-6 209 26 12 (1)   (28)   194    
Intermediate Bond Fund of America, Class R-6 268 9 103 (8)   (15)   151   4  
American Funds Mortgage Fund, Class R-6 179 5 12 (1)   (21)   150   2  
U.S. Government Securities Fund, Class R-6 149 6 9 (1)   (20)   125   3  
American Funds Multi-Sector Income Fund, Class R-6 107 1 3   (5)   101   1  
American High-Income Trust, Class R-6 149 7 58 (8)   (14)   76   5  
American Funds Strategic Bond Fund, Class R-6 80   (6)   74   1  
Capital World Bond Fund, Class R-6 149 4 74 (20)   (10)   49   2  
                1,120        
Total 100.08%       $(47)   $(506)   $2,432   $44   $10
1 Fund did not produce income during the last 12 months.
2 Part of the same “group of investment companies“ as the fund as defined under the Investment Company Act of 1940, as amended.
3 Amount less than one thousand.
American Funds Insurance Series — Target Date Series — Page 10 of 15

American Funds® IS 2015 Target Date Fund
Investment portfolio
September 30, 2022
unaudited
Growth funds 1.34%   Shares Value
(000)
American Funds Global Insight Fund, Class R-6 11,989 $197
AMCAP Fund, Class R-61 3,386 99
Total growth funds (cost: $389,000)     296
Growth-and-income funds 20.67%      
American Mutual Fund, Class R-6 29,109 1,313
Capital World Growth and Income Fund, Class R-6 23,888 1,095
Washington Mutual Investors Fund, Class R-6 20,602 978
The Investment Company of America, Class R-6 17,063 655
Fundamental Investors, Class R-6 9,645 535
Total growth-and-income funds (cost: $4,944,000)     4,576
Equity-income funds 18.37%      
The Income Fund of America, Class R-6 128,165 2,754
Capital Income Builder, Class R-6 22,866 1,312
Total equity-income funds (cost: $4,373,000)     4,066
Balanced funds 11.40%      
American Balanced Fund, Class R-6 61,290 1,642
American Funds Global Balanced Fund, Class R-6 29,748 883
Total balanced funds (cost: $2,959,000)     2,525
Fixed income funds 48.30%      
The Bond Fund of America, Class R-6 171,028 1,921
American Funds Inflation Linked Bond Fund, Class R-6 185,260 1,762
Intermediate Bond Fund of America, Class R-6 139,653 1,723
American Funds Mortgage Fund, Class R-6 151,672 1,347
American Funds Multi-Sector Income Fund, Class R-6 102,659 895
American Funds Strategic Bond Fund, Class R-6 82,541 789
American High-Income Trust, Class R-6 75,996 673
Short-Term Bond Fund of America, Class R-6 66,936 631
U.S. Government Securities Fund, Class R-6 41,500 505
Capital World Bond Fund, Class R-6 29,249 448
Total fixed income funds (cost: $12,057,000)     10,694
Total investment securities 100.08% (cost: $24,722,000)     22,157
Other assets less liabilities (0.08)%     (18)
Net assets 100.00%     $22,139
American Funds Insurance Series — Target Date Series — Page 11 of 15

unaudited
Investments in affiliates2

  Value of
affiliates at
1/1/2022
(000)
Additions
(000)
Reductions
(000)
Net
realized
(loss) gain
(000)
  Net
unrealized
depreciation
(000)
  Value of
affiliates at
9/30/2022
(000)
  Dividend
income
(000)
  Capital gain
distributions
received
(000)
Growth funds 1.34%
American Funds Global Insight Fund, Class R-6 $231 $56 $29 $(2)   $(59)   $197   $  $
AMCAP Fund, Class R-61 115 40 8 (1)   (47)   99     7
                296        
Growth-and-income funds 20.67%
American Mutual Fund, Class R-6 1,150 441 74 3   (204)   1,313   19  
Capital World Growth and Income Fund, Class R-6 959 524 50 (8)   (330)   1,095   17  
Washington Mutual Investors Fund, Class R-6 882 381 62 3   (223)   978   13   26
The Investment Company of America, Class R-6 576 278 16 (2)   (181)   655   8   8
Fundamental Investors, Class R-6 499 213 16 (2)   (159)   535   6   10
                4,576        
Equity-income funds 18.37%
The Income Fund of America, Class R-6 2,376 935 64 (3)   (490)   2,754   62  
Capital Income Builder, Class R-6 1,148 449 26 3   (259)   1,312   28  
                4,066        
Balanced funds 11.40%
American Balanced Fund, Class R-6 1,450 550 6 3   (352)   1,642   20   9
American Funds Global Balanced Fund, Class R-6 763 344 5 (1)   (218)   883   12  
                2,525        
Fixed income funds 48.30%
The Bond Fund of America, Class R-6 1,532 734 37 (1)   (307)   1,921   38   2
American Funds Inflation Linked Bond Fund, Class R-6 1,344 748 97 (2)   (231)   1,762    
Intermediate Bond Fund of America, Class R-6 2,106 735 893 (74)   (151)   1,723   38  
American Funds Mortgage Fund, Class R-6 1,148 411 34 (2)   (176)   1,347   18  
American Funds Multi-Sector Income Fund, Class R-6 940 1 3   (44)   895   10  
American Funds Strategic Bond Fund, Class R-6 846   (57)   789   5  
American High-Income Trust, Class R-6 959 283 405 (49)   (115)   673   37  
Short-Term Bond Fund of America, Class R-6 382 293 14 (1)   (29)   631   6  
U.S. Government Securities Fund, Class R-6 574 109 96 (11)   (71)   505   12  
Capital World Bond Fund, Class R-6 956 338 619 (154)   (73)   448   15  
                10,694        
Total 100.08%       $(313)   $(3,776)   $22,157   $364   $62
1 Fund did not produce income during the last 12 months.
2 Part of the same “group of investment companies“ as the fund as defined under the Investment Company Act of 1940, as amended.
3 Amount less than one thousand.
American Funds Insurance Series — Target Date Series — Page 12 of 15

American Funds® IS 2010 Target Date Fund
Investment portfolio
September 30, 2022
unaudited
Growth-and-income funds 17.55%   Shares Value
(000)
American Mutual Fund, Class R-6 452,523 $20,409
Washington Mutual Investors Fund, Class R-6 314,427 14,923
Capital World Growth and Income Fund, Class R-6 317,326 14,546
The Investment Company of America, Class R-6 290,235 11,139
Fundamental Investors, Class R-6 95,946 5,328
Total growth-and-income funds (cost: $74,393,000)     66,345
Equity-income funds 22.06%      
The Income Fund of America, Class R-6 2,747,527 59,044
Capital Income Builder, Class R-6 424,060 24,333
Total equity-income funds (cost: $93,130,000)     83,377
Balanced funds 9.72%      
American Balanced Fund, Class R-6 970,119 25,989
American Funds Global Balanced Fund, Class R-6 361,739 10,740
Total balanced funds (cost: $43,575,000)     36,729
Fixed income funds 50.76%      
Intermediate Bond Fund of America, Class R-6 3,170,691 39,126
The Bond Fund of America, Class R-6 3,269,407 36,715
American Funds Inflation Linked Bond Fund, Class R-6 2,948,227 28,038
Short-Term Bond Fund of America, Class R-6 2,754,675 25,949
American Funds Mortgage Fund, Class R-6 2,832,614 25,154
American Funds Strategic Bond Fund, Class R-6 1,589,800 15,198
American Funds Multi-Sector Income Fund, Class R-6 1,511,444 13,180
American High-Income Trust, Class R-6 581,113 5,149
Capital World Bond Fund, Class R-6 221,429 3,390
Total fixed income funds (cost: $213,806,000)     191,899
Total investment securities 100.09% (cost: $424,904,000)     378,350
Other assets less liabilities (0.09)%     (323)
Net assets 100.00%     $378,027
American Funds Insurance Series — Target Date Series — Page 13 of 15

unaudited
Investments in affiliates1

  Value of
affiliates at
1/1/2022
(000)
Additions
(000)
Reductions
(000)
Net
realized
loss
(000)
  Net
unrealized
depreciation
(000)
  Value of
affiliates at
9/30/2022
(000)
  Dividend
income
(000)
  Capital gain
distributions
received
(000)
Growth-and-income funds 17.55%
American Mutual Fund, Class R-6 $17,676 $6,933 $944 $(11)   $(3,245)   $20,409   $304   $
Washington Mutual Investors Fund, Class R-6 12,626 6,153 387 (24)   (3,445)   14,923   205   428
Capital World Growth and Income Fund, Class R-6 13,257 7,138 1,208 (112)   (4,529)   14,546   250  
The Investment Company of America, Class R-6 9,469 5,478 652 (103)   (3,053)   11,139   145   150
Fundamental Investors, Class R-6 5,050 2,270 348 (50)   (1,594)   5,328   58   107
                66,345        
Equity-income funds 22.06%
The Income Fund of America, Class R-6 47,346 23,118 784 (43)   (10,593)   59,044   1,328  
Capital Income Builder, Class R-6 20,201 9,178 211 (14)   (4,821)   24,333   533  
                83,377        
Balanced funds 9.72%
American Balanced Fund, Class R-6 22,095 9,676 145 (20)   (5,617)   25,989   323   157
American Funds Global Balanced Fund, Class R-6 10,100 3,663 202 (30)   (2,791)   10,740   154  
                36,729        
Fixed income funds 50.76%
Intermediate Bond Fund of America, Class R-6 49,239 18,585 23,410 (2,024)   (3,264)   39,126   921  
The Bond Fund of America, Class R-6 27,776 14,832   (5,893)   36,715   744   43
American Funds Inflation Linked Bond Fund, Class R-6 19,570 12,260 131 (8)   (3,653)   28,038    
Short-Term Bond Fund of America, Class R-6 22,095 9,109 3,796 (194)   (1,265)   25,949   309  
American Funds Mortgage Fund, Class R-6 20,201 8,250   (3,297)   25,154   348  
American Funds Strategic Bond Fund, Class R-6 16,329   (1,131)   15,198   102  
American Funds Multi-Sector Income Fund, Class R-6 13,862   (682)   13,180   146  
American High-Income Trust, Class R-6 9,469 1,678 4,528 (556)   (914)   5,149   330  
Capital World Bond Fund, Class R-6 9,469 1,994 6,044 (1,475)   (554)   3,390   131  
                191,899        
Total 100.09%       $(4,664)   $(60,341)   $378,350   $6,331   $885
1 Part of the same “group of investment companies“ as the fund as defined under the Investment Company Act of 1940, as amended.
American Funds Insurance Series — Target Date Series — Page 14 of 15

unaudited
Valuation disclosures

Security valuation — The net asset value of each share class of each fund is calculated based on the reported net asset values of the underlying funds in which each fund invests. The net asset value of each underlying fund is calculated based on the policies and procedures of the underlying fund contained in each underlying fund’s statement of additional information. The net asset value per share of each fund and each underlying fund is calculated once daily as of the close of regular trading on the New York Stock Exchange, normally 4 p.m. New York time, each day the New York Stock Exchange is open.
Processes and structure — The series’ board of trustees has designated the series’ investment adviser to make fair value determinations, subject to board oversight. The investment adviser has established a Joint Fair Valuation Committee (the “Fair Valuation Committee”) to administer, implement and oversee the fair valuation process, and to make fair value decisions. The Fair Valuation Committee regularly reviews its own fair value decisions, as well as decisions made under its standing instructions to the investment adviser’s valuation team. The Fair Valuation Committee reviews changes in fair value measurements from period to period and may, as deemed appropriate, update the fair valuation guidelines to better reflect the results of back testing and address new or evolving issues. The Fair Valuation Committee reports any changes to the fair valuation guidelines to the board of trustees. The series’ board and audit committee also regularly review reports that describe fair value determinations and methods. Pricing decisions, processes and controls over security valuation are also subject to additional internal reviews facilitated by the investment adviser’s global risk management group.
Classifications — The series’ investment adviser classifies each fund’s assets and liabilities into three levels based on the method used to value the assets or liabilities. Level 1 values are based on quoted prices in active markets for identical securities. Level 2 values are based on significant observable market inputs, such as quoted prices for similar securities and quoted prices in inactive markets. Level 3 values are based on significant unobservable inputs that reflect the investment adviser’s determination of assumptions that market participants might reasonably use in valuing the securities. The valuation levels are not necessarily an indication of the risk or liquidity associated with the underlying investment.
At September 30, 2022, all of the investment securities held by each fund were classified as Level 1.
Investments are not FDIC-insured, nor are they deposits of or guaranteed by a bank or any other entity, so they may lose value.
Investors should carefully consider investment objectives, risks, charges and expenses. This and other important information is contained in the series prospectus and summary prospectuses, which can be obtained from your financial professional and should be read carefully before investing. You may also call American Funds Service Company (AFS) at (800) 421-4225 or visit the American Funds website at capitalgroup.com. Fund shares offered through American Funds Distributors, Inc.
All Capital Group trademarks mentioned are owned by The Capital Group Companies, Inc., an affiliated company or fund. All other company and product names mentioned are the property of their respective companies.
American Funds Distributors, Inc., member FINRA.
© 2022 Capital Group. All rights reserved.
INGEFP3-988-1122O-S89737 American Funds Insurance Series — Target Date Series — Page 15 of 15