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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Cash flows from operating activities:    
Net loss $ (47,693) $ (54,899)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 2,207 1,875
Amortization of investment discount 94 153
Equity-based compensation 8,179 19,058
Amortization of debt discount and issuance costs 386 9,250
Amortization of debt discount related-party 275 0
Loss (gain) on disposal of property and equipment 74 (202)
Unrealized loss (gain) on equity investments 206 (39)
Gain on extinguishment of debt (3,565) (9,840)
(Increase) decrease in assets:    
Contributions to deferred compensation plan (174) (304)
Accounts receivable (73) (719)
Inventory (245) (527)
Prepaid expense and other (491) 860
Increase (decrease) in liabilities:    
Accounts payable 1,221 1,017
Accrued liabilities and other 962 (436)
Accrued interest (785) (1,059)
Accrued interest from related-party 220 0
Deferred revenue and income 73 93
Deferred compensation (49) 343
Net cash used in operating activities (39,178) (35,376)
Cash flows from investing activities:    
Purchases of equipment (446) (202)
Purchase of marketable securities (27,506) (22,345)
Maturities of marketable securities 34,527 33,601
Net cash provided by investing activities 6,575 11,054
Cash flows from financing activities:    
Proceeds from issuance of common stock 32,872 22,640
Payments on finance leases (1,109) 0
Proceeds from exercise of options 7 1,456
Proceeds from issuance of common stocks under employee purchase plan 184 245
Transaction costs related to debt exchange (192) 0
Payment of debt (6) (6)
Net cash provided by financing activities 31,756 24,335
Effect of exchange rate on cash (64) (69)
Decrease in cash and cash equivalents (911) (56)
Cash and cash equivalents, beginning of period 39,898 35,781
Cash and cash equivalents, end of period 38,987 35,725
Non-cash investing activities:    
Net transfer of instruments (to) from inventory to property and equipment (78) 508
Non-cash financing activities:    
Extinguishment of convertible senior notes through issuance of common stock 10,180 34,545
Convertible notes due from related-party extinguished in connection with the exchange transaction, net of deferred issuance costs 49,624 0
Fair value of new note from related-party issued in connection with the exchange transaction 16,024 0
Fair value of common stock warrant issued to related-party in connection with exchange transaction 3,753 0
Capital contribution from related-party in connection with the exchange transaction 29,847 0
Supplemental cash flow information:    
Interest paid $ 2,214 $ 4,288