v3.22.2.2
Debt - Additional Information (Details)
$ / shares in Units, € in Millions
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 17, 2020
USD ($)
shares
Dec. 24, 2019
USD ($)
TradingDay
Sep. 30, 2022
USD ($)
$ / shares
shares
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Loan
$ / shares
shares
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Dec. 31, 2019
USD ($)
shares
Sep. 30, 2022
EUR (€)
shares
Jul. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
shares
Aug. 28, 2020
shares
Jun. 17, 2014
USD ($)
Debt Instrument [Line Items]                          
Interest rate (as a percent)   6.00%                      
Cash payment made for exchange of notes   $ 200                      
Aggregate payment on debt exchange   55,200,000       $ 69,000,000              
Gain on debt extinguishment               $ 55,100,000          
Adjusted equity component of convertible notes exchange               $ 38,400,000          
Common stock, Authorized shares | shares 61,666,666   61,666,666   61,666,666     13,333,333 61,666,666   61,666,666 13,333,333  
Derivative liability reclassified to equity $ 18,300,000                        
Income tax effects on equity transactions             $ 4,400,000            
Interest expense     $ 7,465,000 $ 7,167,000 $ 22,501,000 $ 22,697,000              
Non Convertible Debt                          
Debt Instrument [Line Items]                          
Principal     24,900,000   24,900,000                
Fair value of debt     20,500,000   $ 20,500,000       € 18.2        
Number Of Loans | Loan         14                
Non Convertible Debt | Finland S Ministry Of Finance Rate                          
Debt Instrument [Line Items]                          
Residual payment amount                   $ 50,000,000      
Non Convertible Debt | Finland S Ministry Of Finance Rate | Biotie                          
Debt Instrument [Line Items]                          
Cash     14,500,000   $ 14,500,000                
Convertible Senior Notes due 2021                          
Debt Instrument [Line Items]                          
Principal amount of debt exchanged   $ 276,000,000.0                      
Interest rate (as a percent)   1.75%                     1.75%
Principal amount denomination for debt conversion   $ 1,000                      
Principal                         $ 345,000,000
Debt instrument, principal amount outstanding   $ 69,000,000.0 69,000,000.0   69,000,000.0                
Debt issuance costs     $ 7,500,000   7,500,000                
Reclassification of derivative liability to equity, net of tax         1,300,000                
Debt issuance costs allocated to liability component         6,200,000                
Debt issuance cost associated with exchange, written off         $ 1,200,000                
Convertible Senior Secured Notes due 2024                          
Debt Instrument [Line Items]                          
Interest rate (as a percent)   6.00% 6.00%   6.00%       6.00%        
Principal amount of debt issued for exchange   $ 750                      
Principal   $ 207,000,000.0                      
Debt instrument, principal amount outstanding     $ 207,000,000   $ 207,000,000           $ 207,000,000    
Notes maturity date   Dec. 01, 2024     Dec. 01, 2024                
Interest payment in shares, percentage of daily volume-weighted average price   95.00%                      
Notes frequency of periodic payment         semi-annually in arrears                
Interest in shares of common stock, threshold trading days | TradingDay   10                      
Initial conversion rate of common stock         47.6190                
Initial conversion price of convertible notes into common stock (in dollars per share) | $ / shares     $ 21.00   $ 21.00                
Principal amount of Notes or an integral multiple thereof in which holder may repurchase the Notes     $ 1,000   $ 1,000                
Stockholders' equity, reverse stock split         1-for-6                
Debt instrument conversion threshold stock price percentage   130.00%                      
Repurchase principal amount, Percentage   100.00%                      
Debt default, non payment of interest, period   30 days                      
Debt default, failure to convert notes, period   5 days                      
Debt default, non-compliance with covenants, period   60 days                      
Fair value of derivative liability   $ 59,400,000                 $ 37,000    
Debt discount   $ 75,100,000                      
Interest expense     7,200,000   $ 21,100,000                
Effective interest rate on liability component (as a percent)   18.13%                      
Debt fair value amount     157,300,000   157,300,000                
Debt issuance costs     $ 5,700,000   $ 5,700,000                
Convertible Senior Secured Notes due 2024 | Minimum                          
Debt Instrument [Line Items]                          
Debt default, non-payment of outstanding principal   $ 30,000,000.0                      
Debt default, failure to pay final judgements   $ 30,000,000.0                      
Debt default, percentage of principal outstanding required for immediate payment   25.00%