Deferred Credit, Operating Lease Liability

No definition available.

Name:	rgls_DeferredCreditOperatingLeaseLiability
Namespace Prefix:	rgls_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Initial Direct Cost Liability

+ References

No definition available.

+ Details

Name:	rgls_InitialDirectCostLiability
Namespace Prefix:	rgls_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Nonrefundable Lease Cost for Assignment

+ References

No definition available.

+ Details

Name:	rgls_NonrefundableLeaseCostForAssignment
Namespace Prefix:	rgls_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Number of Operating Lease Contracts

+ References

No definition available.

+ Details

Name:	rgls_NumberOfOperatingLeaseContracts
Namespace Prefix:	rgls_
Data Type:	xbrli:decimalItemType
Balance Type:	na
Period Type:	instant

- Definition

Rented Area

+ References

No definition available.

+ Details

Name:	rgls_RentedArea
Namespace Prefix:	rgls_
Data Type:	dtr-types:areaItemType
Balance Type:	na
Period Type:	instant

- Definition

For an unclassified balance sheet, the accumulated amortization, as of the reporting date, which represents the periodic charge to earnings of initial direct costs which have been deferred and are being allocated over the lease term in proportion to the recognition of rental income.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 30
-Section 25
-Paragraph 10
-URI https://asc.fasb.org/extlink&oid=123408481&loc=SL77919138-209958

Reference 2: http://fasb.org/us-gaap/role/ref/otherTransitionRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 20
-Section 25
-Paragraph 16
-URI https://asc.fasb.org/extlink&oid=123394419&loc=d3e40588-112709

Reference 3: http://fasb.org/us-gaap/role/ref/otherTransitionRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 20
-Section 35
-Paragraph 2
-URI https://asc.fasb.org/extlink&oid=123394697&loc=d3e40879-112712

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

Name:	us-gaap_LesseeLeaseDescriptionLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 6
-URI https://asc.fasb.org/extlink&oid=128292326&loc=SL77918701-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

+ References

+ Details

Name:	us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease having initial or remaining lease term in excess of one year to be paid in remainder of current fiscal year.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 6
-URI https://asc.fasb.org/extlink&oid=128292326&loc=SL77918701-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Term of lessee's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 3
-Subparagraph (a)(3)
-URI https://asc.fasb.org/extlink&oid=128292326&loc=SL77918673-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseTermOfContract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	instant

- Definition

Net rentable area for properties owned.

+ References

No definition available.

+ Details

Name:	us-gaap_NetRentableArea
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:areaItemType
Balance Type:	na
Period Type:	instant

- Definition

Amount of lessee's right to use underlying asset under operating lease.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 45
-Paragraph 1
-Subparagraph (a)
-URI https://asc.fasb.org/extlink&oid=123391704&loc=SL77918627-209977

+ Details

Name:	us-gaap_OperatingLeaseRightOfUseAsset
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Details

Name:	srt_RealEstateAndAccumulatedDepreciationDescriptionOfPropertyAxis=rgls_PriorPremisesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_RealEstateAndAccumulatedDepreciationDescriptionOfPropertyAxis=rgls_CampusPointLeaseMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

Leases (Narrative) (Details) $ in Thousands	Feb. 11, 2021 USD ($) ft² contract	Sep. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)	Apr. 30, 2021 USD ($)	Dec. 31, 2020 USD ($)	Jul. 01, 2019 USD ($)	Jun. 19, 2019 ft²
Lessee, Lease, Description [Line Items]
Remaining liability to be paid		$ 191
Base rent payments due 2021		776
ROU asset		2,174	$ 2,564
Operating lease payments due		$ 2,868
Prior Premises
Lessee, Lease, Description [Line Items]
Net rentable area \| ft²							8,727
Term of contract			2 years 6 months
Remaining liability to be paid					$ 400
Base rent payments due 2021			$ 400
Initial direct cost liability						$ 800
ROU asset						600
Deferred credit, operating lease liabilities						$ 200
Campus Point Lease
Lessee, Lease, Description [Line Items]
Term of contract	60 months
Initial direct cost liability	$ 3,200			$ 100
ROU asset	3,000			100
Deferred credit, operating lease liabilities	$ 200
Rented area \| ft²	13,438
Operating lease payments due	$ 3,800
Nonrefundable lease cost for assignment	$ 60
Number of operating lease contracts \| contract	3
Deferred cost of liability				$ 200