The following table sets forth the computation of the basic and diluted net loss per share for the three and nine months ended September 30, 2022 and 2021 (in thousands, except share and per share data):


	Three Months Ended September 30,						Nine Months Ended September 30,
	2022			2021			2022			2021
Numerator:
Net loss	$	(21,235	)	$	(18,651	)	$	(60,887	)	$	(51,275	)
Denominator:
Weighted-average shares used to compute net loss per share, basic and diluted		33,684,261			29,491,857			31,481,948			26,663,209
Net loss per share, basic and diluted	$	(0.63	)	$	(0.63	)	$	(1.93	)	$	(1.92	)

For the three and nine months ended September 30, 2022, 4,000,000 pre-funded warrants to purchase the Company's shares of common stock, issued in the May 2022 PIPE financing (see Note 8), were included in the basic and diluted net loss per share calculation.

Potential dilutive securities that were not included in the diluted per share calculations because they would be anti-dilutive were as follows:


	As of September 30,
	2022		2021
Stock options issued and outstanding under the 2019 Equity Incentive Plan and 2015 Stock Plan		2,972,047		1,982,298
Estimated shares issuable under the 2019 ESPP		17,650		23,569
RSUs subject to future vesting		27,000		40,500
Total		3,016,697		2,046,367