$ 19,800,000

Revenue Recognition, Multiple-deliverable Arrangements [Line Items]

$ 10,750,000

through the later of 10 years after first commercial sale of a licensed product in such country, expiration of the last licensed patent covering a licensed product

Royalty payment, percentage

5.00%

Revenue Recognition, Multiple-deliverable Arrangements [Line Items]

Payment of milestone amount

$ 5,000,000

Commitments and Contingencies - Additional Information (Detail) - USD ($)		9 Months Ended		12 Months Ended
	May 31, 2005	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2020	Dec. 31, 2021
Siegfried campaign [Member] \| Purchase Commitment [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Cash paid		$ 19,800,000
Lonza Campaign [Member] \| Purchase Commitment [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Cash paid					$ 9,500,000
Product [Member] \| Bristol-Myers Squibb Company [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Company made an upfront payment	$ 10,750,000
Obliged to make milestone payments		$ 14,750,000
License expiration period		through the later of 10 years after first commercial sale of a licensed product in such country, expiration of the last licensed patent covering a licensed product
Cost of product sales		$ 8,100,000	$ 2,800,000
Product [Member] \| Bristol-Myers Squibb Company [Member] \| Minimum [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Royalty payment, percentage		5.00%
Product [Member] \| Bristol-Myers Squibb Company [Member] \| Maximum [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Royalty payment, percentage		9.00%
Product [Member] \| Bristol-Myers Squibb Company [Member] \| ITCI National Democratic Alliance Member [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Payment of milestone amount				$ 5,000,000