v3.22.2.2
Leases - Narrative (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jul. 01, 2020
USD ($)
ft²
item
Jun. 19, 2020
USD ($)
room
May 31, 2022
USD ($)
ft²
period
building
Sep. 30, 2022
USD ($)
lease
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
lease
Sep. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2021
USD ($)
Leases                  
Number of operating leases | lease       2   2      
Operating lease, expense       $ 6,800 $ 5,300 $ 18,000 $ 15,900    
Finance lease liabilities- current       2,583   2,583     $ 3,000
Finance lease liabilities- noncurrent       18,675   18,675     20,053
Aggregate rent, Initial term       271,188   271,188      
Operating lease ROU assets       104,901   104,901     $ 77,421
Operating Lease, Liability       111,019   111,019      
Finance Lease, Right-of-Use Asset       0   0      
Research and development       165,462 130,845 462,802 390,840    
MassBio                  
Leases                  
Lessee, Finance Lease, Existence of Option to Terminate [true false]   true              
Finance lease cost       $ 400 $ 400 $ 1,200 $ 1,300    
Written notice required for early lease termination   24 months              
Number of dedicated rooms provided for gene therapy AADC program | room   4              
Guaranteed lease payment due at onset of the lease agreement   $ 15,000              
Guaranteed lease payments due annually   3,000              
Present value of guaranteed lease payments   $ 41,400              
Finance lease, term of contract   12 years 6 months              
Research and development               $ 41,400  
Minimum                  
Leases                  
Operating lease, term of contract       1 month 6 days   1 month 6 days      
Maximum                  
Leases                  
Operating lease, term of contract       16 years 8 months 12 days   16 years 8 months 12 days      
Renewal term       15 years   15 years      
Hopewell Campus                  
Leases                  
Operating lease, term of contract 15 years                
Area of real estate property | ft² 220,500                
Renewal term 10 years                
Number of renewable terms | item 2                
Lessee, Operating Lease, Existence of Option to Extend [true false] true                
Aggregate rent, Initial term $ 111,500                
Percent of market rate 95.00%                
Warren Premises                  
Leases                  
Operating lease, term of contract     17 years            
Number of buildings leased | building     2            
Area of real estate property | ft²     360,000            
Renewal term     5 years            
Number of renewable terms | period     3            
Lessee, Operating Lease, Existence of Option to Extend [true false]     true            
Aggregate rent, Initial term     $ 163,000            
Base rent abatement period     3 years            
Base rent abatement     $ 18,600            
Aggregate rent net of base rate abatement, initial term     144,400            
Allowance for lease improvements     36,200            
Commitment to fund construction account     3,600            
Payment due from lessor at issuance of temporary certificate of occupancy     5,000            
Operating lease ROU assets     28,900            
Operating Lease, Liability     $ 28,900