v3.22.2.2
Stock award plan - (Tables)
9 Months Ended
Sep. 30, 2022
Share-based Payment Arrangement [Abstract]  
Summary of stock option activity

    

    

    

Weighted-

    

  

Weighted-

average

Aggregate

average

remaining

intrinsic

Number of

exercise

contractual

value(in 

options

price

term

thousands)

 

Outstanding at December 31, 2021

 

10,772,582

$

43.66

 

  

 

  

Granted

 

1,539,070

38.38

 

  

 

  

Exercised

 

(456,399)

29.00

 

  

 

  

Forfeited/Cancelled

 

(376,832)

49.39

 

  

 

  

Outstanding at September 30, 2022

 

11,478,421

$

43.35

 

6.59

years

$

111,769

Vested or Expected to vest at September 30, 2022

 

3,757,239

$

47.88

 

8.29

years

$

24,594

Exercisable at September 30, 2022

 

7,369,484

$

40.83

 

5.62

years

$

84,800

Schedule of assumptions used to estimate fair values of grants made on the date of grant

    

Nine months ended

    

September 30, 2022

Risk-free interest rate

 

1.55% - 3.26%

Expected volatility

 

55.33% - 73.56%

Expected term

 

5.5 years

Summary of information on the Company's restricted stock

Restricted Stock Awards and Units

Weighted

Average

Grant

Number of

Date

    

Shares

    

Fair Value

Unvested at December 31, 2021

1,519,831

$

55.43

Granted

 

1,615,182

38.28

Vested

 

(493,847)

50.14

Forfeited

 

(152,222)

46.85

Unvested at September 30, 2022

 

2,488,944

$

45.84

Schedule of share-based compensation expense recorded in the statement of operations

Three Months Ended September 30, 

Nine Months Ended September 30, 

    

2022

    

2021

    

2022

    

2021

Research and development

$

15,063

$

13,048

$

41,896

$

40,216

Selling, general and administrative

 

13,607

 

12,823

 

41,093

 

37,061

Total

$

28,670

$

25,871

$

82,989

$

77,277