Exhibit 107

Calculation of Filing Fee Tables

Form S-1

(Form Type)

Amylyx Pharmaceuticals, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities and Carry Forward Securities

 

                 
     Security
type
  Security
class
title
  Fee
calculation
or carry
forward
rule
  Amount
registered
  Proposed
maximum
offering
price per
share
  Proposed
maximum
aggregate
offering
price(1)(2)
 

Fee

rate

  Amount of
registration
fee (3)
 
Newly Registered Securities
                 

Fees to Be

Paid

  Equity   Common Stock, par value $0.0001 per share   457(o)       $41,054,984   0.0001102   $4,524.26
                 

Fees

Previously

Paid

               
 
Carry Forward Securities
                 

Carry

Forward

Securities

               
           
    Total Offering Amounts      $41,054,984     $4,524.26
           
    Total Fees Previously Paid         
           
    Total Fee Offsets         
           
    Net Fee Due (4)                $4,524.26

 

(1)

Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the “Securities Act”).

(2)

Includes the offering price of shares that the underwriters may purchase pursuant to an option to purchase additional shares.

(3)

Calculated pursuant to Rule 457(o) based on an estimate of the proposed maximum aggregate offering price.

(4)

The Registrant previously registered securities having a proposed maximum aggregate offering price of $205,275,000 on its Registration Statement on Form S-1 (File No. 333-267730), which was declared effective by the Securities and Exchange Commission on October 6, 2022. In accordance with Rule 462(b) under the Securities Act, an additional number of securities having a proposed maximum offering price of $41,054,984 is hereby registered, which includes securities issuable upon the exercise of the underwriters’ option to purchase additional shares.