FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person *
Orwin John A

(Last) (First) (Middle)
21823 30TH DRIVE SE

(Street)
BOTHELL WA 98021

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Seagen Inc. [ SGEN ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
05/13/2022
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/13/2022   A (1)   1,503 (2) A $ 0 29,003 (3) D  
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $ 135.63 05/13/2022   A   3,676   05/13/2023 05/13/2032 Common Stock 3,676 $ 0 3,676 D  
Explanation of Responses:
1. These restricted stock units will be settled in common stock upon vesting.
2. These restricted stock units shall vest in full on May 13, 2023.
3. Amount of securities beneficially owned following reported transactions includes restricted stock units subject to vesting.
By: /s/ Jennifer Prosba For: John A. Orwin 05/17/2022
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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                                   POWER OF ATTORNEY

        The undersigned hereby constitutes and appoints Jean Liu, Todd Simpson,
and Elizabeth Bekiroglu, each of them, his or her true and lawful attorney-in-
fact to:

(1)     execute for and on behalf of the undersigned, in the undersigned's
        capacity as an officer, director, and/or person who holds more than 10%
        of the stock of Seagen Inc. (the "Company"), Forms 3, Forms 4 and Forms
        5 in accordance with Section 16(a) of the Securities Exchange Act of
        1934, as amended (the "Exchange Act"), and the rules thereunder;

(2)     do and perform any and all acts for and on behalf of the undersigned
        which may be necessary or desirable to complete and execute any such
        Forms 3, Forms 4 or Forms 5 and timely file any such forms with the
        United States Securities and Exchange Commission and any other
        authority; and

(3)     take any other action of any type whatsoever in connection with the
        foregoing which, in the opinion of such attorney-in-fact, may be of
        benefit to, in the best interest of, or legally required by, the
        undersigned, it being understood that the documents executed by such
        attorney-in-fact on behalf of the undersigned, pursuant to this Power of
        Attorney shall be in such form and shall contain such terms and
        conditions as such attorney-in-fact may approve in his or her
        discretion.

        The undersigned hereby grants to each such attorney-in-fact full power
and authority to do and perform any and every act and thing whatsoever
requisite, necessary or proper to be done in the exercise of any of the rights
and powers herein granted, as fully to all intents and purposes as the
undersigned might or could do if personally present, with full power of
substitution or revocation, hereby ratifying and confirming all that such
attorney-in-fact, or his or her substitute or substitutes, shall lawfully do or
cause to be done pursuant to this power of attorney. The undersigned
acknowledges that the foregoing attorneys-in-fact, in serving in such capacity
at the request of the undersigned, are not assuming, nor is the Company
assuming, any of the undersigned's responsibilities to comply with Section 16 of
the Exchange Act.

        This Power of Attorney shall remain in full force and effect until the
undersigned is no longer required to file Forms 3, Forms 4, and Forms 5 with
respect to the undersigned's holdings of and transactions in securities issued
by the Company, unless earlier revoked by the undersigned in a signed writing
delivered to the attorneys-in-fact.

        The undersigned has caused this Power of Attorney to be executed as of
this 14th day of May 2021.

                                   /s/ John Orwin
                                   -----------------------------------------
                                   John Orwin




                        SUBSTITUTE POWER OF ATTORNEY

Pursuant to a written power of attorney, a copy of which was previously filed
(the "Power of Attorney"), the undersigned, Jean Liu, has been constituted and
appointed true and lawful attorney-in-fact, with full power of substitution and
revocation, to do and perform every act and thing whatsoever requisite,
necessary, or proper to be done in the exercise of the rights and powers granted
in said Power of Attorney, by the following individual:

John Orwin

Know all by these presents, that, pursuant to the powers granted to the
undersigned in the Power of Attorney, the undersigned hereby constitutes and
appoints each of Jessica Nielsen Causey and Jennifer Prosba as a substitute to
the undersigned attorney-in-fact, with full power of substitution or revocation,
and with full power and authority to do and perform every act and thing
whatsoever requisite, necessary, or proper to be done in the exercise of the
rights and powers granted to the undersigned in said Power of Attorney. For the
avoidance of doubt, the foregoing appointment shall not serve as a revocation of
the powers granted to the undersigned in the Power of Attorney.

This Substitute Power of Attorney shall remain in full force and effect unless
and until revoked by the undersigned.

IN WITNESS WHEREOF, the undersigned has caused this Substitute Power of Attorney
to be executed as of this 2nd day of September, 2021.

Signature: /s/ Jean Liu
-------------------------------
Name: Jean Liu