FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person *
Saxonov Serge

(Last) (First) (Middle)
C/O 10X GENOMICS, INC.
6230 STONERIDGE MALL ROAD

(Street)
PLEASANTON CA 94588

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
10x Genomics, Inc. [ TXG ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
Chief Executive Officer
3. Date of Earliest Transaction (Month/Day/Year)
09/07/2021
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Class A Common Stock 08/26/2021   G V 360 D $ 0 4,498 (1) I See Footnote (2)
Class A Common Stock 09/07/2021   M (3)   5,209 A $ 5.04 903,677 (4) D  
Class A Common Stock 09/07/2021   M (3)   9,791 A $ 11.48 913,468 D  
Class A Common Stock 09/07/2021   S (3)   700 D $ 184.4942 (5) 912,768 D  
Class A Common Stock 09/07/2021   S (3)   1,200 D $ 185.5035 (6) 911,568 D  
Class A Common Stock 09/07/2021   S (3)   2,702 D $ 186.7371 (7) 908,866 D  
Class A Common Stock 09/07/2021   S (3)   2,025 D $ 187.4494 (8) 906,841 D  
Class A Common Stock 09/07/2021   S (3)   1,414 D $ 188.5079 (9) 905,427 D  
Class A Common Stock 09/07/2021   S (3)   2,800 D $ 189.8108 (10) 902,627 D  
Class A Common Stock 09/07/2021   S (3)   3,759 D $ 190.4398 (11) 898,868 D  
Class A Common Stock 09/07/2021   S (3)   400 D $ 191.125 (12) 898,468 D  
Class A Common Stock               89,960 I See Footnote (13)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $ 5.04 09/07/2021   M (3)     5,209   (14) 11/02/2028 Class A Common Stock 5,209 $ 0 68,948 D  
Stock Option (right to buy) $ 11.48 09/07/2021   M (3)     9,791   (15) 05/10/2029 Class A Common Stock 9,791 $ 0 58,130 D  
Explanation of Responses:
1. As of June 4, 2021, 4,858 shares of Class A Common Stock were held by the Andromeda Trust, for which the Reporting Person and his spouse serve as trustees (the "Andromeda Trust"), and which shares were received upon transfer from the Reporting Person. Following the disposition by gift of 360 shares on August 26, 2021, the Andromeda Trust holds 4,498 shares of Class A Common Stock.
2. The shares are held by the Andromeda Trust.
3. The option exercises and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into by the Reporting Person.
4. Reflects the transfer by the Reporting Person of 4,858 shares of Class A Common Stock to the Andromeda Trust, as referenced in footnote (1).
5. This transaction was executed in multiple trades at prices ranging from $184.00 to $184.855. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
6. This transaction was executed in multiple trades at prices ranging from $185.015 to $185.98. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
7. This transaction was executed in multiple trades at prices ranging from $186.105 to $187.095. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
8. This transaction was executed in multiple trades at prices ranging from $187.11 to $188.075. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
9. This transaction was executed in multiple trades at prices ranging from $188.155 to $189.06. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
10. This transaction was executed in multiple trades at prices ranging from $189.20 to $190.02. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
11. This transaction was executed in multiple trades at prices ranging from $190.08 to $191.00. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
12. This transaction was executed in multiple trades at prices ranging from $191.09 to $191.16. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
13. The shares are held by the Y/S Descendants' Trust, for which the Reporting Person serves as trustee.
14. This option, originally for 250,000 shares, of which 181,052 have been exercised, vested as to one forty-eighth of the shares on October 1, 2018, and one-forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.
15. This option, originally for 145,786 shares, of which 87,656 have been exercised, vested as to one forty-eighth of the shares on May 1, 2019, and one-forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date.
/s/ Eric S. Whitaker, as Attorney-in-Fact 09/09/2021
** Signature of Reporting Person Date
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